Evidence map›Paper›PMID 31289200›Full record

ArticleHaematologica2020

Atherogenic lipid stress induces platelet hyperactivity through CD36-mediated hyposensitivity to prostacyclin: the role of phosphodiesterase 3A.

Martin Berger, Zaher Raslan, Ahmed Aburima, Simbarashe Magwenzi, Katie S Wraith, Benjamin E J Spurgeon, Matthew S Hindle, Robert Law, Maria Febbraio, Khalid M Naseem

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Targeting Cysteine Oxidation in Thrombotic Disorders.Antioxidants (Basel, Switzerland) · 2024
    Review
  9. Article
  10. Review
  11. Review
  12. Platelet Innate Immune Receptors and TLRs: A Double-Edged Sword.International journal of molecular sciences · 2021
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Martin BergerCentre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK.
Zaher RaslanDiscovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Ahmed AburimaCentre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK.
Simbarashe MagwenziCentre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK.
Katie S WraithCentre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK.
Benjamin E J SpurgeonDiscovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Matthew S HindleDiscovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Robert LawCentre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK.
Maria FebbraioSchool of Dentistry, University of Alberta, Edmonton, AB, Canada.
Khalid M NaseemCentre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Hull, UK k.naseem@leeds.ac.uk.
University of Leeds · GBHull York Medical School · GBUniversity of Alberta · CAUniversity of Hull · GB

Funding

British Heart Foundation PG/11/37/28884British Heart Foundation PG/12/49/29441British Heart Foundation PG/13/90/20578British Heart Foundation RG/16/5/32250
6 · The paper itself

Abstract

Prostacyclin (PGI

Indexed as

Blood PlateletsEpoprostenolAnimalsCyclic Nucleotide Phosphodiesterases, Type 3HumansLipidsMicePlatelet ActivationPlatelet AggregationCyclic Nucleotide Phosphodiesterases, Type 3EpoprostenolLipids

Identifiers

PMID31289200
PMCPMC7049344
OpenAlexW2958122699

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.