Evidence map›Paper›PMID 31289187›Full record

ArticlemBio2019

Deletion of Plasmodium falciparum Protein RON3 Affects the Functional Translocation of Exported Proteins and Glucose Uptake.

Leanne M Low, Yvonne Azasi, Emma S Sherling, Matthias Garten, Joshua Zimmerberg, Takafumi Tsuboi, Joseph Brzostowski, Jianbing Mu, Michael J Blackman, Louis H Miller

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. TgRON3 Links the Moving Junction to Microneme Secretion and Parasite Motility in Toxoplasma gondii.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  4. Selective targeting ofAntimicrobial agents and chemotherapy · 2026
    Article
  5. Article
  6. Review
  7. mBio · 2025
    Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. The direct binding ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Article
  14. Review
  15. Plasmepsin-like Aspartyl Proteases inPathogens (Basel, Switzerland) · 2021
    Article
  16. Article
  17. Review
  18. How Malaria Parasites Acquire Nutrients From Their Host.Frontiers in cell and developmental biology · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Leanne M Low *Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, Maryland, USA.
Yvonne Azasi *Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, Maryland, USA.
Emma S Sherling *Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, Maryland, USA.
Matthias GartenSection on Integrative Biophysics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, USA.
Joshua ZimmerbergSection on Integrative Biophysics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, USA.
Takafumi TsuboiDivision of Malaria Research, Proteo-Science Center, Ehime University, Matsuyama, Ehime, Japan.
Joseph BrzostowskiLIG Imaging Facility, NIAID, NIH, Rockville, Maryland, USA.
Jianbing MuLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, Maryland, USA.
Michael J BlackmanMalaria Biochemistry Laboratory, The Francis Crick Institute, London, United Kingdom.
Louis H MillerLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, Maryland, USA lmiller@niaid.nih.gov.
National Institute of Allergy and Infectious Diseases · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USEhime University · JPThe Francis Crick Institute · GB

Funding

Membrane Remodeling in Viral Infection, Parasite Replication, and Traumatic Brain InjuryZIAHD001409 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ZIMMERBERG, JOSHUA · 2009 to 2025
$29.9M
Malaria Parasite Receptors And Host Cell LigandsZIAAI000241 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MILLER, LOUIS · 2009 to 2025
$15.3M
Medical Research Council FC001043Wellcome Trust FC001043
6 · The paper itself

Abstract

The survival of

Indexed as

Gene DeletionHost-Parasite InteractionsTranslocation, GeneticAntigens, NeoplasmBiological TransportErythrocytesGlucoseHumansMalaria, FalciparumPlasmodium falciparumProtein TransportProtozoan ProteinsAntigens, NeoplasmGlucoseProtozoan ProteinsRON3 protein, Plasmodium falciparummalariaparasite proteinsparasitophorous vacuolar spacePTEX

Identifiers

PMID31289187
PMCPMC6747712
OpenAlexW2958925103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.