Evidence map›Paper›PMID 31289186›Full record

ArticlemBio2019

The Extracellular Domain of the β

Laura C Ristow, Vy Tran, Kevin J Schwartz, Lillie Pankratz, Andrew Mehle, John-Demian Sauer, Rodney A Welch

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. LDL receptor-mediated endocytosis ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Microorganisms · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Virulence and Pathogenicity Properties ofPathogens (Basel, Switzerland) · 2019
    Review
  16. Toxins · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Laura C RistowDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Vy TranDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Kevin J SchwartzDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Lillie PankratzDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Andrew MehleDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-6060-4330
John-Demian SauerDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-9367-794X
Rodney A WelchDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA rawelch@wisc.edu.
University of Wisconsin–Madison · US

Funding

GRADUATE TRAINING IN MOLECULAR BIOSCIENCEST32GM007215 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HULL, CHRISTINA M · 1985 to 2018
$22.5M
Identification and Characterization of Genes Required for Listeria monocytogenes Cytosolic SurvivalR01AI137070 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI SAUER, JOHN-DEMIAN · 2018 to 2022
$2.9M
Modulating the Inflammasome to Generate Robust Cell Mediated ImmunityR01CA188034 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI SAUER, JOHN-DEMIAN · 2015 to 2019
$1.7M
Identifying host factors and the mechanisms used to control influenza virus replicationR21AI125897 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI MEHLE, ANDREW · 2016 to 2017
$425k
NCI NIH HHS R01 CA188034NIAID NIH HHS R01 AI137070NIAID NIH HHS R21 AI125897NIGMS NIH HHS T32 GM007215
6 · The paper itself

Abstract

The

Indexed as

Aggregatibacter actinomycetemcomitansBacterial ToxinsCD18 AntigensCell LineCell SurvivalEscherichia coliEscherichia coli ProteinsExotoxinsGenetic Complementation TestHemolysin ProteinsHumansMonocytesMutationProtein BindingU937 CellsBacterial ToxinsCD18 AntigensEscherichia coli ProteinsExotoxinsHemolysin ProteinsHlya protein, E colileukotoxincytotoxicityhemolysinintegrinsleukotoxinRTX toxin

Identifiers

PMID31289186
PMCPMC6747720
OpenAlexW2957221220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.