Evidence map›Paper›PMID 31289175›Full record

ArticlemBio2019

Positional Dynamics and Glycosomal Recruitment of Developmental Regulators during Trypanosome Differentiation.

Balázs Szöőr, Dorina V Simon, Federico Rojas, Julie Young, Derrick R Robinson, Timothy Krüger, Markus Engstler, Keith R Matthews

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. The trypanosomatid dynamin-like protein associates with glycosomes.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Structure, Properties, and Function of Glycosomes inFrontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Balázs SzöőrInstitute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom Balazs.Szoor@ed.ac.uk keith.matthews@ed.ac.uk.
Dorina V SimonInstitute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Federico RojasInstitute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Julie YoungInstitute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Derrick R RobinsonCNRS, Microbiology Fundamental and Pathogenicity, MFP UMR 5234, University of Bordeaux, Bordeaux, France.
Timothy KrügerCell and Developmental Biology, University of Würzburg Biozentrum, Würzburg, Germany.
Markus EngstlerCell and Developmental Biology, University of Würzburg Biozentrum, Würzburg, Germany.
Keith R MatthewsInstitute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom Balazs.Szoor@ed.ac.uk keith.matthews@ed.ac.uk.
University of Edinburgh · GBUniversity of Würzburg · DECentre National de la Recherche Scientifique · FR

Funding

Wellcome Trust 103740/Z/14/Z
6 · The paper itself

Abstract

Glycosomes are peroxisome-related organelles that compartmentalize the glycolytic enzymes in kinetoplastid parasites. These organelles are developmentally regulated in their number and composition, allowing metabolic adaptation to the parasite's needs in the blood of mammalian hosts or within their arthropod vector. A protein phosphatase cascade regulates differentiation between parasite developmental forms, comprising a tyrosine phosphatase,

Indexed as

Life Cycle StagesMicrobodiesOptical ImagingPhosphoprotein PhosphatasesProtein Tyrosine PhosphatasesProtozoan ProteinsSignal TransductionTrypanosoma brucei bruceiPhosphoprotein PhosphatasesProtein Tyrosine PhosphatasesProtozoan Proteinsdevelopmentdifferentiationglycosomeorganelleparasitetrypanosome

Identifiers

PMID31289175
PMCPMC6747725
OpenAlexW2960653791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.