Evidence map›Paper›PMID 31289122›Full record

ArticleThe Journal of biological chemistry2019

Cynthia Olotu, Felix Lehmensiek, Bastian Koch, Martina Kiefmann, Ann-Kathrin Riegel, Sven Hammerschmidt, Rainer Kiefmann

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Frontiers in microbiology · 2022
    Article
  4. Possible role of purinergic signaling in COVID-19.Molecular and cellular biochemistry · 2021
    Review
  5. P2 Purinergic Signaling in the Distal Lung in Health and Disease.International journal of molecular sciences · 2020
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Cynthia OlotuCenter for Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 22051 Hamburg, Germany c.olotu@uke.de.ORCID 0000-0001-9272-7386
Felix LehmensiekCenter for Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 22051 Hamburg, Germany.
Bastian KochCenter for Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 22051 Hamburg, Germany.
Martina KiefmannCenter for Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 22051 Hamburg, Germany.
Ann-Kathrin RiegelCenter for Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 22051 Hamburg, Germany.
Sven HammerschmidtInstitute of Genetics and Functional Genomics, Department of Molecular Genetics and Infection Biology, University of Greifswald, Felix-Hausdorff-Strasse 8, 17489 Greifswald, Germany.ORCID 0000-0002-6382-6681
Rainer KiefmannCenter for Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 22051 Hamburg, Germany.
Universität Hamburg · DEUniversität Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial pneumonia is a global health challenge that causes up to 2 million deaths each year. Purinergic signaling plays a pivotal role in healthy alveolar epithelium. Here, we used fluorophore-based analysis and live-cell calcium imaging to address the question of whether the bacterial pathogen

Indexed as

A549 CellsAdenosine TriphosphateAlveolar Epithelial CellsAnimalsCalcium SignalingCells, CulturedHumansMaleRatsRats, Sprague-DawleyReceptors, Purinergic P2Y2Streptococcus pneumoniaeAdenosine TriphosphateReceptors, Purinergic P2Y2alveolar epithelial cellsATPcalciumlungpneumoniapurinergic receptorreceptor internalizationreceptor phosphorylationStreptococcusStreptococcus pneumoniaevirulence

Identifiers

PMID31289122
PMCPMC6709641
OpenAlexW2959939650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.