Evidence map›Paper›PMID 31289106›Full record

ArticleDrug metabolism and disposition: the biological fate of chemicals2019

Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate.

Amit Kumar, D Fernando Estrada

Open access · bronzeAbstract read
In one paragraph

Article in Drug metabolism and disposition: the biological fate of chemicals, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Characterization of a CYP107 family vitamin DArchives of biochemistry and biophysics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Amit KumarDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Science, University at Buffalo, Buffalo New York.
D Fernando EstradaDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Science, University at Buffalo, Buffalo New York dfestrad@buffalo.edu.
University at Buffalo, State University of New York · US

Funding

Crystallographic and NMR studies of the Human Cytochrome P450 enzyme responsible for inactivating vitamin DR00GM112862 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI ESTRADA, DAVID FERNANDO · 2016 to 2018
$747k
NIGMS NIH HHS R00 GM112862
6 · The paper itself

Abstract

Metabolic deactivation of 1,25(OH)

Indexed as

AdrenodoxinAllosteric RegulationCalcitriolCarbonCatalytic DomainEnzyme AssaysHydroxycholecalciferolsHydroxylationMagnetic Resonance SpectroscopyOxidation-ReductionRecombinant ProteinsVitamin D3 24-HydroxylaseAdrenodoxinalfacalcidolCalcitriolCarbonCyp24a1 protein, ratHydroxycholecalciferolsRecombinant ProteinsVitamin D3 24-Hydroxylase

Identifiers

PMID31289106
PMCPMC7184192
OpenAlexW2958249298

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.