Evidence map›Paper›PMID 31289065›Full record

ArticleBMJ open2019

Is maternal weight gain between pregnancies associated with risk of large-for-gestational age birth? Analysis of a UK population-based cohort.

Nida Ziauddeen, Sam Wilding, Paul J Roderick, Nicholas S Macklon, Nisreen A Alwan

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Change in modifiable maternal characteristics and behaviours between consecutive pregnancies and offspring adiposity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020
    Pooled it
  3. The impact of interpregnancy weight change on perinatal outcomes in women and their children: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020
    Pooled it
  4. Pooled it
  5. Examining Interpregnancy Weight Change Across a Birthing Population in Aotearoa, New Zealand.The Australian & New Zealand journal of obstetrics & gynaecology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Nida ZiauddeenSchool of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.ORCID 0000-0002-8964-5029
Sam WildingSchool of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Paul J RoderickSchool of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Nicholas S MacklonDepartment of Obstetrics and Gynaecology, University of Copenhagen, Zealand University Hospital, Roskilde, Denmark.
Nisreen A AlwanSchool of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.ORCID 0000-0002-4134-8463
Primary Health Care · QAUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Copenhagen · DK

Funding

Academy of Medical Sciences HOP001\1060Wellcome Trust
6 · The paper itself

Abstract

objectiveMaternal overweight and obesity during pregnancy increases the risk of large-for-gestational age (LGA) birth and childhood obesity. We aimed to investigate the association between maternal weight change between subsequent pregnancies and risk of having a LGA birth.

designPopulation-based cohort.

settingRoutinely collected antenatal healthcare data between January 2003 and September 2017 at University Hospital Southampton, England.

participantsHealth records of women with their first two consecutive singleton live-birth pregnancies were analysed (n=15 940). PRIMARY OUTCOME MEASURE: Risk of LGA, recurrent LGA and new LGA births in the second pregnancy.

resultsOf the 15 940 women, 16.0% lost and 47.7% gained weight (≥1 kg/m

conclusionsLosing weight after an LGA birth was associated with a reduced LGA risk in the next pregnancy in overweight women, while interpregnancy weight gain was associated with an increased new LGA risk. Preventing weight gain between pregnancies is an important measure to achieve better maternal and offspring outcomes.

Indexed as

AdultBody Mass IndexFemaleFetal MacrosomiaGestational Weight GainHumansInfant, NewbornObesityParityPregnancyPregnancy ComplicationsPrenatal CareProspective StudiesRisk FactorsUnited Kingdomlarge-for-gestational ageobesitypregnancypregnancy outcomeweight gain

Identifiers

PMID31289065
PMCPMC6615839
OpenAlexW2961134872

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.