Evidence map›Paper›PMID 31289044›Full record

ArticleCMAJ open

Prenatal bed rest in developed and developing regions: a systematic review and meta-analysis.

Brittany Matenchuk, Rshmi Khurana, Chenxi Cai, Normand G Boulé, Linda Slater, Margie H Davenport

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Fetal death: Expert consensus of the French College of Obstetricians and Gynecologists.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Guideline
  2. Pooled it
  3. Trial
  4. Review
  5. The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  6. Review
  7. Cost-effectiveness of cervical length screening and progesterone treatment to prevent spontaneous preterm delivery in Sweden.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2022
    Article
  8. Physical Activity Behaviors and Barriers in Multifetal Pregnancy: What to Expect When You're Expecting More.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Brittany MatenchukProgram for Pregnancy and Postpartum Health (Matenchuk, Cai, Davenport) and Physical Activity and Diabetes Laboratory (Boulé, Davenport), Faculty of Kinesiology, Sport, and Recreation, University of Alberta; Departments of Medicine (Khurana) and Obstetrics & Gynecology (Khurana), University of Alberta; Women and Children's Health Research Institute (Cai, Davenport), University of Alberta; John W. Scott Health Sciences Library (Slater), University of Alberta; Alberta Diabetes Institute (Boulé, Davenport), University of Alberta, Edmonton, Alta.
Rshmi KhuranaProgram for Pregnancy and Postpartum Health (Matenchuk, Cai, Davenport) and Physical Activity and Diabetes Laboratory (Boulé, Davenport), Faculty of Kinesiology, Sport, and Recreation, University of Alberta; Departments of Medicine (Khurana) and Obstetrics & Gynecology (Khurana), University of Alberta; Women and Children's Health Research Institute (Cai, Davenport), University of Alberta; John W. Scott Health Sciences Library (Slater), University of Alberta; Alberta Diabetes Institute (Boulé, Davenport), University of Alberta, Edmonton, Alta.
Chenxi CaiProgram for Pregnancy and Postpartum Health (Matenchuk, Cai, Davenport) and Physical Activity and Diabetes Laboratory (Boulé, Davenport), Faculty of Kinesiology, Sport, and Recreation, University of Alberta; Departments of Medicine (Khurana) and Obstetrics & Gynecology (Khurana), University of Alberta; Women and Children's Health Research Institute (Cai, Davenport), University of Alberta; John W. Scott Health Sciences Library (Slater), University of Alberta; Alberta Diabetes Institute (Boulé, Davenport), University of Alberta, Edmonton, Alta.
Normand G BouléProgram for Pregnancy and Postpartum Health (Matenchuk, Cai, Davenport) and Physical Activity and Diabetes Laboratory (Boulé, Davenport), Faculty of Kinesiology, Sport, and Recreation, University of Alberta; Departments of Medicine (Khurana) and Obstetrics & Gynecology (Khurana), University of Alberta; Women and Children's Health Research Institute (Cai, Davenport), University of Alberta; John W. Scott Health Sciences Library (Slater), University of Alberta; Alberta Diabetes Institute (Boulé, Davenport), University of Alberta, Edmonton, Alta.
Linda SlaterProgram for Pregnancy and Postpartum Health (Matenchuk, Cai, Davenport) and Physical Activity and Diabetes Laboratory (Boulé, Davenport), Faculty of Kinesiology, Sport, and Recreation, University of Alberta; Departments of Medicine (Khurana) and Obstetrics & Gynecology (Khurana), University of Alberta; Women and Children's Health Research Institute (Cai, Davenport), University of Alberta; John W. Scott Health Sciences Library (Slater), University of Alberta; Alberta Diabetes Institute (Boulé, Davenport), University of Alberta, Edmonton, Alta.
Margie H DavenportProgram for Pregnancy and Postpartum Health (Matenchuk, Cai, Davenport) and Physical Activity and Diabetes Laboratory (Boulé, Davenport), Faculty of Kinesiology, Sport, and Recreation, University of Alberta; Departments of Medicine (Khurana) and Obstetrics & Gynecology (Khurana), University of Alberta; Women and Children's Health Research Institute (Cai, Davenport), University of Alberta; John W. Scott Health Sciences Library (Slater), University of Alberta; Alberta Diabetes Institute (Boulé, Davenport), University of Alberta, Edmonton, Alta. margie.davenport@ualberta.ca.
Women and Children’s Health Research Institute · CAUniversity of Alberta · CADavenport University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBed rest is prescribed by most maternity health care professionals for high-risk pregnancy complications, but the impact of bed rest at home and in hospital has not been explored. Our aim was to quantify the influence of bed rest on maternal/fetal health outcomes in developed and developing regions.

methodsWe conducted a systematic review and meta-analysis of randomized controlled trials. We conducted a structured search through MEDLINE, Embase, CINAHL, Web of Science and the Cochrane Library through Mar. 7, 2019. Trials comparing standard care to standard care plus bed rest after 20 weeks' gestation were assessed. Outcomes included infant birth weight, being small for gestational age, gestational age, premature or very premature birth, perinatal death, admission to the neonatal intensive care unit, preterm rupture of membranes, hypertensive disorders of pregnancy, preeclampsia and gestational diabetes mellitus.

resultsWe identified 1191 publications, of which 43 were assessed for eligibility. Sixteen publications reporting on 14 unique studies (2608 women, 3328 infants) were included in the analysis. Overall, maternal/newborn outcomes were similar between women on bed rest and those not on bed rest. In subgroup analyses of developed and developing regions, length of gestation was shorter with bed rest (weighted mean difference -0.77 wk, 95% confidence interval [CI] -1.26 to -0.27,

interpretationIn developed regions, treatment of complicated pregnancies with more than 1 week of bed rest results in worse newborn outcomes. Additional studies are required to determine whether bed rest or hospital admission improves outcomes in developing regions.

Identifiers

PMID31289044
PMCPMC6620175
OpenAlexW2958201913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.