SynthesisAnnals of clinical microbiology and antimicrobials2019
Prevalence of Shigella species and its drug resistance pattern in Ethiopia: a systematic review and meta-analysis.
Synthesis in Annals of clinical microbiology and antimicrobials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 5 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 5 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Medicinal Plants Used for Combating Human Bacterial Diseases in Ethiopia: A Systematic Review.TheScientificWorldJournal · 2026Pooled it
- Molecular epidemiology of extended-spectrum beta-lactamases and carbapenemases-producing Shigella in Africa: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Prevalence of Salmonella and Shigella species and their multidrug resistance patterns among pediatric populations in Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- The increasing antimicrobial resistance ofPathogens and global health · 2023Pooled it
- Pooled it
- Use of standard definitions for the extent of antibiotic resistance in bacteria: a systematic review and framework for future consensus definitions.JAC-antimicrobial resistance · 2026Review
- "Molecular Characterization of Extended Spectrum Beta-Lactamase Resistance in Pediatric Shigella Isolates in Egypt".Biochemical genetics · 2025Article
- Prevalence of Salmonella, Shigella, and parasites in food handlers at Bahir Dar university, Ethiopia.BMC infectious diseases · 2025Article
- Prevalence, antimicrobial susceptibility pattern and associated factors of Salmonella and Shigella among under five children with diarrhea attending Bule Hora University Teaching Hospital, Bule Hora, West Guji, Ethiopia.BMC infectious diseases · 2025Article
- Prevalence and changing antimicrobial resistance profiles of Shigella spp. isolated from diarrheal patients in Kolkata during 2011-2019.PLoS neglected tropical diseases · 2024Article
- Insights from Shigella bacteriophage genomes analysis.Bioinformation · 2024Article
- The genomic epidemiology of shigellosis in South Africa.Nature communications · 2023Article
- Situational analysis of antimicrobial resistance, laboratory capacities, surveillance systems and containment activities in Ethiopia: A new and one health approach.One health (Amsterdam, Netherlands) · 2023Review
- Prevalence of Antibiotic-ResistantAntibiotics (Basel, Switzerland) · 2023Review
- Flavonoids and Phenolic Acids from Aerial Part ofMolecules (Basel, Switzerland) · 2023Article
- Prevalence, antimicrobial resistance pattern, and associated factors ofFrontiers in public health · 2023Article
- Antimicrobial Susceptibility Patterns ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023Article
- Prevalence and Antimicrobial-Resistant Features ofInterdisciplinary perspectives on infectious diseases · 2023Review
- Prevalence of Multidrug-Resistant and Extended-Spectrum Beta-Lactamase-ProducingAntibiotics (Basel, Switzerland) · 2022Review
- Occurrence of drug-resistant enteric bacteria and associated factors among food handlers of the Mass Catering Center: A laboratory-based cross-sectional study.Italian journal of food safety · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundShigella species are a major cause of dysentery and may attribute for death worldwide. Currently antibiotic resistance became the critical challenges for management of infectious disease. The aim was to conduct a systematic review and meta-analysis of Shigella species and its drug resistance pattern in Ethiopia.
methodsA comprehensive literature search was conducted through internet searches using database of MEDLINE, PubMed, Google scholar, EMBASE, HINARI, Cochrane Library and reference lists of previous prevalence studies from January 1999 to November 2018. Results were presented in forest plot, tables and figures with 95% CI. The Cochrane Q test and I
resultsThe pooled prevalence of Shigella species in Ethiopia was 6.6% (95% CI 4.7-8.8). In the subgroup analysis, the highest prevalence was observed among patients in Health facility (8.5%, 95% CI 6.2-11.5) whereas the lowest prevalence was observed in Community based studies (1.6%, 95% CI 0.8-3.4). In addition, Shigella species were highly resistant to ampicillin, amoxicillin, erythromycin and multi-drug resistant (MDR) with the pooled resistance proportions of 83.1% (95% CI 75.7-88.6), 84.1% (95% CI 75.6-90.1), 86.5% (95% CI 70.9-94.4) and 83.2% (95% CI 77.1-87.9), respectively. On the other hand, comparably low resistance pattern was reported for ciprofloxacin 8.9% (95% CI 6.0-12.8), ceftriaxone 9.3% (95% CI 3.9-20.5), and norfloxacin 8.2% (95% CI 3.8-16.6) and gentamycin 17.3% (95% CI 11.2-25.9). Subgroup analyses indicated that study years were associated with a decreasing Shigella prevalence over time (p = 0.002).
conclusionThe pooled estimate showed high burden of Shigella infection and its high proportion of drug resistance pattern to ampicillin, amoxicillin and erythromycin in Ethiopia. Therefore, initiating and scale up of performing drug susceptibility test for each shigellosis case, educate the community and health care providers on appropriate use of antibiotics need to be considered and strengthened.
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