Evidence map›Paper›PMID 31288761›Full record

ArticleBMC nephrology2019

Clinical characteristics and outcome of HIV infected patients with chronic kidney disease in Sub Saharan Africa: an example from in Cameroon.

Marie Patrice Halle, Noel Essomba, Hilaire Djantio, Germaine Tsele, Hermine Fouda, Namme Henri Luma, Enow Gloria Ashuntantang, Folefack Francois Kaze

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Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marie Patrice HalleFaculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon. patricehalle@yahoo.fr.
Noel EssombaFaculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
Hilaire DjantioHigher Institute of Health Sciences, Université des Montagnes, Bangangte, Cameroon.
Germaine TseleFaculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
Hermine FoudaDepartment of Internal Medicine, Douala General Hospital, PO Box: 4856, Douala, Cameroon.
Namme Henri LumaDepartment of Internal Medicine, Douala General Hospital, PO Box: 4856, Douala, Cameroon.
Enow Gloria AshuntantangFaculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
Folefack Francois KazeFaculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is one of the major complications of Human immune deficiency Virus (HIV) and a risk factor for poor outcome of these patients. We aimed to describe the profile and outcome of HIV positive patients with CKD in Douala general hospital in Cameroon.

methodsHIV positive patients with CKD referred to the nephrologist from January 2007 to March 2013 were included. Socio demographic, clinical (history and stage of HIV, comorbidities, baseline nephropathy, used of c-ART), para clinical data at referral (serum urea, creatinine, full blood count, CD4 count, serum calcium, phosphorus, albumin), dialysis initiation and outcome at 1 year were collected from medical records. GFR was estimated using Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations. CKD was defined and classified according to the Kidney Disease Improving Global Outcomes (KDIGO 2012).

resultsWe included 156 patients (51.3% men) with a mean age of 45.4 ± 12.1 years. Hypertension (36.5%), diabetes (17.9%) and Hepatitis C (7.7%) were the main comorbidities. HIV associated nephropathy (27.6%), chronic glomerulonephritis (15.4%) diabetes (14.1%) and hypertension (13.5%) were the leading causes of kidney disease. Before referral HIV status was known by 109 (69.9%) patients, with 76 (69.7%) being on c-ART. Median CD

conclusionHIV patients with CKD were referred late with high morbidity and need for urgent hemodialysis. HIVAN was the main etiology of CKD and mortality rate was high mainly due to the absence of c-ART at referral.

Indexed as

AdultCameroonFemaleHIV InfectionsHumansMaleMiddle AgedRenal Insufficiency, ChronicRetrospective StudiesTreatment OutcomeCameroonChronic kidney diseaseDoualaHuman immune deficiency virus

Identifiers

PMID31288761
PMCPMC6617860

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