ArticleBMC infectious diseases2019
Clinical parameters and outcomes of necrotizing soft tissue infections secondary to gastrointestinal fistulas.
Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Adjunctive hyperbaric oxygen treatment for necrotising soft-tissue infections: A systematic review and meta-analysis.Diving and hyperbaric medicine · 2021Pooled it
- Prognostic value of inflammatory and metabolic markers in Fournier's gangrene: a single-center retrospective analysis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Research on risk assessment and predictive model for gastrointestinal fistula after gastrectomy based on F-index scoring system.BMC gastroenterology · 2026Article
- Necrotizing myofasciitis: management in the emergency department using PoCUS. A case report.Journal of ultrasound · 2025Article
- [Repair strategies and clinical outcomes for complex cervico-occipital wounds].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2025Observational
- The Association of Coloproctology of Great Britain and Ireland consensus guidelines in emergency colorectal surgery.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2021Article
- Necrotizing Soft Tissue Infections, the Challenge Remains.Frontiers in surgery · 2021Article
- Getting it Right the First Time: Frozen Sections for Diagnosing Necrotizing Soft Tissue Infections.World journal of surgery · 2021Article
- Technique Advances in Enteroatmospheric Fistula Isolation After Open Abdomen: A Review and Outlook.Frontiers in surgery · 2020Review
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundNecrotizing soft tissue infections (NSTIs) is severe surgical infections which can occur following trauma or abdominal surgery. NSTIs secondary to gastrointestinal (GI) fistula is a rare but severe complication.
methodsA retrospective cohort study was performed on all subjects presenting with GI fistulas associated NSTIs were included. Clinical characteristics, microbiological profile, operations performed, and outcomes of patients were analyzed.
resultsBetween 2014 and 2017, 39 patients were finally enrolled. The mean age were 46.9 years and male were the dominant. For the etiology of fistula, 25 (64.1%) of the patients was due to trauma. Overall, in-hospital death occurred in 15 (38.5%) patients. Microbiologic findings were obtained from 31 patients and Klebsiella pneumoniae was the most common species (41.0%). Eight patients were treated with an open abdomen; negative pressure wound therapy was used in 33 patients and only 2 patients received hyperbaric oxygen therapy. Younger age and delayed abdominal wall reconstruction repair were more common in trauma than in non-trauma. Non-survivors had higher APACHE II score, less source control< 48 h and lower platelet count on admission than survivors. Multiple organ dysfunction syndrome, multidrug-resistant organisms and source control failure were the main cause of in-hospital mortality.
conclusionsTrauma is the main cause of GI fistulas associated NSTIs. Sepsis continues to be the most important factor related to mortality. Our data may assist providing enlightenment for quality improvement in these special populations.
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