ArticleBMC infectious diseases2019
A lung abscess caused by secondary syphilis - the utility of polymerase chain reaction techniques in transbronchial biopsy: a case report.
Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Asymptomatic Neurosyphilis Presenting With Bilateral Pulmonary Nodules: A Case Report.Respirology case reports · 2025Article
- Syphilis as Rare Cause of Pyogenic Liver Abscess.Emerging infectious diseases · 2025Article
- Secondary syphilis sparing palms and soles, with pulmonary involvement.Revista do Instituto de Medicina Tropical de Sao Paulo · 2025Article
- Syphilitic pneumonia: case report and systematic review.Le infezioni in medicina · 2025Article
- An Update on the Status of Direct Testing forJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024Review
- Pulmonary syphilis with a cicatricial variant of organizing pneumonia: a case report.BMC pulmonary medicine · 2023Article
- A Case of Secondary Pulmonary Syphilis - The Utility of mNGS in Bronchoalveolar Lavage Fluid: A Case Report.Infection and drug resistance · 2022Article
- A case of pulmonary nodules in a patient living with HIV diagnosed with secondary syphilis.BMJ case reports · 2021Article
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Authors and funding
14 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Japan and other countries, the number of patients with syphilis is increasing year by year. Recently, the cases of the pulmonary involvement in patients with secondary syphilis have been reported. However, it is still undetermined how to obtain a desirable specimen for a diagnosis of the pulmonary involvement, and how to treat it if not cured. CASE PRESENTATION: A 34-year-old man presented with cough and swelling of the right inguinal nodes. A physical examination revealed erythematous papular rash over the palms, soles and abdomen. A 4 cm mass in the right lower lobe of the lung was detected on computed tomography. He was diagnosed as having secondary syphilis, because he was tested positive for the rapid plasma reagin and Treponema pallidum hemagglutination assay. Amoxycillin and probenecid were orally administered for 2 weeks. Subsequently, rash and serological markers were improved, however, the lung mass remained unchanged in size. Transbronchial biopsy (TBB) confirmed the pulmonary involvement of syphilis using polymerase chain reaction techniques (tpp47- and polA-PCR). Furthermore, following surgical resection revealed the lung mass to be an abscess.
conclusionsTo our knowledge, this is the first surgically treated case of a lung abscess caused by syphilis, which was diagnosed by PCR techniques in TBB. This report could propose a useful diagnostic method for the pulmonary involvement of syphilis.
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