Evidence map›Paper›PMID 31288721›Full record

ReviewCurrent molecular medicine2019

Stem Cells as a Resource for Treatment of Infertility-related Diseases.

Jing Wang, Chi Liu, Masayuki Fujino, Guoqing Tong, Qinxiu Zhang, Xiao-Kang Li, Hua Yan

Abstract readReview
In one paragraph

Review in Current molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Utilization of Stem Cells in Medicine: A Narrative Review.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Testicular immunity.Molecular aspects of medicine · 2024
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Polycystic ovary syndrome: emerging stem cell therapies.Revista da Associacao Medica Brasileira (1992) · 2024
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing WangReproductive Center, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Chi LiuDivision of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan.
Masayuki FujinoDivision of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan.
Guoqing TongReproductive Center, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Qinxiu ZhangDepartment of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xiao-Kang LiDivision of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan.
Hua YanReproductive Center, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide, infertility affects 8-12% of couples of reproductive age and has become a common problem. There are many ways to treat infertility, including medication, intrauterine insemination, and in vitro fertilization. In recent years, stem-cell therapy has raised new hope in the field of reproductive disability management. Stem cells are self-renewing, self-replicating undifferentiated cells that are capable of producing specialized cells under appropriate conditions. They exist throughout a human's embryo, fetal, and adult stages and can proliferate into different cells. While many issues remain to be addressed concerning stem cells, stem cells have undeniably opened up new ways to treat infertility. In this review, we describe past, present, and future strategies for the use of stem cells in reproductive medicine.

Indexed as

Stem Cell TransplantationAdult Germline Stem CellsCell DifferentiationCellular Reprogramming TechniquesEmbryonic Stem CellsFemaleHumansInduced Pluripotent Stem CellsInfertility, FemaleInfertility, MaleMaleMesenchymal Stem Cell TransplantationOocytesOvaryReproductive Techniques, AssistedSpermatocytesfertilizationICSIInfertilityIUIIVFstem cells.World Health Organization (WHO)

Identifiers

PMID31288721
PMCPMC6806537

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.