SynthesisProceedings. Biological sciences2019
On the diverse and opposing effects of nutrition on pathogen virulence.
Synthesis in Proceedings. Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- On the diverse and opposing effects of nutrition on pathogen virulence.Proceedings. Biological sciences · 2019Pooled it
- Swimming behavior of Daphnia dentifera is influenced by Australozyma monospora infection.PloS one · 2026Article
- How do parasites and predators choose their victim? A trade-off between quality and vulnerability across antagonistic interactions.Biological reviews of the Cambridge Philosophical Society · 2025Review
- Article
- Order of arrival and nutrient supply alter outcomes of co-infection with two fungal pathogens.Proceedings. Biological sciences · 2024Article
- Evaluating host diet effects on microparasites by measuring the stoichiometry of infrapopulations one cell at a time.Ecology and evolution · 2024Article
- Review
- Marine transmissible cancer navigates urbanized waters, threatening spillover.Proceedings. Biological sciences · 2024Article
- Naturally-associated bacteria modulate Orsay virus infection of Caenorhabditis elegans.PLoS pathogens · 2024Article
- Feeding the fever: Complex host-pathogen dynamics along continuous resource gradients.Ecology and evolution · 2023Review
- Natural variation in host feeding behaviors impacts host disease and pathogen transmission potential.Ecology and evolution · 2023Article
- Resource limitation has a limited impact on the outcome of virus-fungus co-infection in an insect host.Ecology and evolution · 2022Article
- Microbial evolution and transitions along the parasite-mutualist continuum.Nature reviews. Microbiology · 2021Review
- Viral susceptibility across host species is largely independent of dietary protein to carbohydrate ratios.Journal of evolutionary biology · 2021Article
- Testing evolutionary explanations for the lifespan benefit of dietary restriction in fruit flies (Drosophila melanogaster).Evolution; international journal of organic evolution · 2021Article
- Article
- Host density drives viral, but not trypanosome, transmission in a key pollinator.Proceedings. Biological sciences · 2020Article
- Article
- The Malnutritional Status of the Host as a Virulence Factor for New Coronavirus SARS-CoV-2.Frontiers in medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Climate change and anthropogenic activity are currently driving large changes in nutritional availability across ecosystems, with consequences for infectious disease. An increase in host nutrition could lead to more resources for hosts to expend on the immune system or for pathogens to exploit. In this paper, we report a meta-analysis of studies on host-pathogen systems across the tree of life, to examine the impact of host nutritional quality and quantity on pathogen virulence. We did not find broad support across studies for a one-way effect of nutrient availability on pathogen virulence. We thus discuss a hypothesis that there is a balance between the effect of host nutrition on the immune system and on pathogen resources, with the pivot point of the balance differing for vertebrate and invertebrate hosts. Our results suggest that variation in nutrition, caused by natural or anthropogenic factors, can have diverse effects on infectious disease outcomes across species.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.