Evidence map›Paper›PMID 31288582›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2019

Potential multifunctional agents with anti-hepatoma and anti-inflammation properties by inhibiting NF-кB activation.

Chang-Ming Su, Gui-Ge Hou, Chun-Hua Wang, Hong-Qin Zhang, Cheng Yang, Mei Liu, Yun Hou

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Novel 2-phenyl-4H-chromen derivatives: synthesis and anti-inflammatory activity evaluationJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
  3. Article
  4. Article
  5. Potential anti-neuroinflammatory NF-кB inhibitors based on 3,4-dihydronaphthalen-1(2Journal of enzyme inhibition and medicinal chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chang-Ming Sua School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China , Binzhou Medical University , Yantai , PR China.
Gui-Ge Houa School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China , Binzhou Medical University , Yantai , PR China.
Chun-Hua Wanga School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China , Binzhou Medical University , Yantai , PR China.
Hong-Qin Zhangb School of Basic Medical Sciences , Binzhou Medical University , Yantai , PR China.
Cheng Yangb School of Basic Medical Sciences , Binzhou Medical University , Yantai , PR China.
Mei Liuc Pharmacy Department , The Second People's Hospital of Dongying , Dongying , PR China.
Yun Houb School of Basic Medical Sciences , Binzhou Medical University , Yantai , PR China.
Binzhou Medical University · CNBinzhou University · CNXian Yang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhibition of NF-κB signalling has been demonstrated as a therapeutic option in treating inflammatory diseases and cancers. Herein, we synthesized novel dissymmetric 3,5-bis(arylidene)-4-piperidones (BAPs,

Indexed as

Anti-Inflammatory AgentsAntineoplastic AgentsApoptosisCarcinoma, HepatocellularCell LineCell Line, TumorHumansInflammationLiver NeoplasmsMolecular Docking SimulationNF-kappa BAnti-Inflammatory AgentsAntineoplastic AgentsNF-kappa B3,5-Bis(arylidene)-4-piperidonesanti-canceranti-inflammationmolecular dockingNF-κB inhibitor

Identifiers

PMID31288582
PMCPMC6691761
OpenAlexW2961429654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.