Evidence map›Paper›PMID 31288496›Full record

ArticleInternational journal of molecular sciences2019

Novel Salicylic Acid Analogs Induce a Potent Defense Response in Arabidopsis.

Ian Arthur Palmer, Huan Chen, Jian Chen, Ming Chang, Min Li, Fengquan Liu, Zheng Qing Fu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Bioactive Compounds and Antioxidant Activity ofMolecules (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Salicylic Acid Signalling in Plants.International journal of molecular sciences · 2020
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ian Arthur PalmerDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.
Huan ChenDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.
Jian ChenDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.
Ming ChangDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.
Min LiDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.
Fengquan LiuInstitute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base of Ministry of Science and Technology, Nanjing 210014, China. fqliu20011@sina.com.
Zheng Qing FuDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA. zfu@mailbox.sc.edu.ORCID 0000-0003-1519-6192

Funding

National Science Foundation 1464527National Science Foundation IOS-1758994
6 · The paper itself

Abstract

The master regulator of salicylic acid (SA)-mediated plant defense, NPR1 (NONEXPRESSER OF PR GENES 1) and its paralogs NPR3 and NPR4, act as SA receptors. After the perception of a pathogen, plant cells produce SA in the chloroplast. In the presence of SA, NPR1 protein is reduced from oligomers to monomers, and translocated into the nucleus. There, NPR1 binds to TGA, TCP, and WRKY transcription factors to induce expression of plant defense genes. A list of compounds structurally similar to SA was generated using ChemMine Tools and its Clustering Toolbox. Several of these analogs can induce SA-mediated defense and inhibit growth of

Indexed as

Disease ResistanceArabidopsisArabidopsis ProteinsGene Expression Regulation, PlantMolecular StructureProtein BindingSalicylic AcidSignal TransductionArabidopsis ProteinsSalicylic AcidanalogsNPR1NPR3NPR4PR1Pseudomonas syringaesalicylic acid

Identifiers

PMID31288496
PMCPMC6651783

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.