ArticleProceedings of the National Academy of Sciences of the United States of America1988
Sequence analyses of herpesviral enzymes suggest an ancient origin for human sexual behavior.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- HSV-2 serology can be predictive of HIV epidemic potential and hidden sexual risk behavior in the Middle East and North Africa.Epidemics · 2010Pooled it
- Review
- The Role of aDNA in Understanding the Coevolutionary Patterns of Human Sexually Transmitted Infections.Genes · 2018Review
- Insights from paleomicrobiology into the indigenous peoples of pre-colonial America - a review.Memorias do Instituto Oswaldo Cruz · 2014Review
- Genomics, the origins of agriculture, and our changing microbe-scape: time to revisit some old tales and tell some new ones.American journal of physical anthropology · 2013Review
- The evolution of infectious agents in relation to sex in animals and humans: brief discussions of some individual organisms.Annals of the New York Academy of Sciences · 2011Review
- Novel less-abundant viral microRNAs encoded by herpes simplex virus 2 latency-associated transcript and their roles in regulating ICP34.5 and ICP0 mRNAs.Journal of virology · 2009Article
- Role of viruses in human evolution.American journal of physical anthropology · 2003Review
- Retrotransposition and herpesvirus evolution.Virus genes · 1995Review
- The RR1 gene of herpes simplex virus type 1 is uniquely trans activated by ICP0 during infection.Journal of virology · 1993Article
- Random mutagenesis of the thymidine kinase gene of varicella-zoster virus.Journal of virology · 1992Article
- Short, duplicated sequence indicative of the recombinogenicity of the junction between a unique and an inverted repeat sequence in the S component of the herpes simplex virus type 1 genome.Journal of virology · 1989Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Comparison of the amino acid sequences of the deoxythymidine kinases of herpes simplex (HSV) and of marmoset herpes viruses (MHV) suggests a divergence time of 8 to 10 million years ago for HSV-1 and -2. Like MHV, HSV-1 and -2 cause local infections in their natural hosts, and direct contact between two individuals during the brief period of infectivity is needed for transmission. Because B virus, a nearer relative of HSV, depends on both oral and genital routes of transmission, we postulate that ancestral HSV (aHSV) was similar, and that for HSV-1 and -2 to diverge, genital and oral sites had to become microbiologically somewhat isolated from each other, while oral--oral and genital--genital contact had to be facilitated to maintain both aHSV strains. We propose that acquisition of continual sexual attractiveness by the ancestral human female and the adoption of close face-to-face mating, two hallmarks of human sexual behavior, provided the conditions for the divergence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.