ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2020
Principles and Issues for Physical Frailty Measurement and Its Clinical Application.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Developing an HIV-specific falls risk prediction model with a novel clinical index: a systematic review and meta-analysis method.BMC infectious diseases · 2024Pooled it
- Physical Fitness and All-Cause Mortality in Older Adults.JAMA network open · 2026Article
- The association of frailty with health care costs using the FRAIL scale.Aging clinical and experimental research · 2026Article
- Frailty in Adults with CKD and Validation of the Kidney Failure Risk Equation in Frailty Subgroups.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Frailty Prevalence and Characterization Among Kidney Transplant Candidates in Spain: A Multicenter Study.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Gerontologic Biostatistics and Data Science: Aging Research in the Era of Big Data.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Review
- Clinical Application of Frailty in the Evaluation of Solid Organ Transplant Patients.Current transplantation reports · 2024Article
- Validation of the Self-Reported Edmonton Frail Scale - Acute Care in Patients ≥ 65 Years Undergoing Surgery.Perioperative care and operating room management · 2024Article
- The Association of Frailty and Neighborhood Disadvantage with Emergency Department Visits and Hospitalizations in Older Adults.Journal of general internal medicine · 2024Observational
- Prevalence and feasibility of assessing the frailty phenotype among hemodialysis patients in a dialysis unit.BMC nephrology · 2023Article
- Higher baseline resting metabolic rate is associated with 1-year frailty decline among older adults residing in an urban area.BMC geriatrics · 2023Article
- A crosswalk of commonly used frailty scales.Journal of the American Geriatrics Society · 2023Article
- Substitution of self-reported measures for objectively assessed grip strength and slow walk in the Physical Frailty Phenotype: ramifications for validity.BMC geriatrics · 2023Article
- Frailty assessment as part of transplant listing: yes, no or maybe?Clinical kidney journal · 2023Review
- Development and validation of a physical frailty phenotype index-based model to estimate the frailty index.Diagnostic and prognostic research · 2023Article
- Trends in post-acute care and outcomes for Medicare beneficiaries hospitalized for heart failure between 2008 and 2015.Journal of the American Geriatrics Society · 2023Article
- Using a Claims-Based Frailty Index to Investigate Frailty, Survival, and Healthcare Expenditures among Older Adults Hospitalized for COVID-19 at an Academic Medical Center.The Journal of frailty & aging · 2023Article
- Review
- Moving toward clinical implementation of the physical frailty phenotype in kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022Article
- Exploring Shared Effects of Multisensory Impairment, Physical Dysfunction, and Cognitive Impairment on Physical Activity: An Observational Study in a National Sample.Journal of aging and physical activity · 2022Observational
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
Abstract
introduction"Frailty" has attracted attention for its promise of identifying vulnerable older adults, hence its potential use to better tailor geriatric health care. There remains substantial controversy, however, regarding its nature and ascertainment. Recent years have seen a proliferation of frailty assessment methods. We argue that the development of frailty assessments should be grounded in "validation"-the process of substantiating that a measurement accurately and precisely measures what it intends, identify unresolved measurement issues, and highlight measurement-related considerations for clinical practice.
methodsPrinciples for validating frailty measures are elucidated. We follow principles-articulated, for example, by Borsboom-in which a construct must be clearly defined and then analyses undertaken to substantiate that a measurement accurately and precisely measures what it intends. Key elements are content validity, criterion validity, and construct validity, with an emphasis on the latter.
resultsWe illustrate the principles for a physical frailty phenotype construct.
conclusionsUnresolved conceptual issues include the roles of intersecting concepts such as cognition, disease severity, and disability in frailty measurement, conceptualization of frailty as a state versus a continuum, and the potential need for dynamic measures and systems concepts in furthering understanding of frailty. Clinical considerations include needs to distinguish interventions designed to address frailty "symptoms" versus underlying physiology, improve "prefrailty" measures intended to screen individuals early in their frailty progression, address feasibility demands, and further visioning followed by rigorous efficacy research to address the landscape of potential uses of frailty assessment in clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.