Evidence map›Paper›PMID 31287333›Full record

SynthesisExpert review of clinical pharmacology2019

Adjuvant trastuzumab regimen for HER2-positive early-stage breast cancer: a systematic review and meta-analysis.

Anne Julienne Genuino, Usa Chaikledkaew, Due Ong The, Thanyanan Reungwetwattana, Ammarin Thakkinstian

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Expert review of clinical pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  16. Trastuzumab aggravates radiation induced cardiotoxicity in mice.American journal of cancer research · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Anne Julienne Genuinoa Faculty of Pharmacy, Faculty of Medicine Ramathibodi Hospital, Faculty of Medicine Siriraj Hospital, Faculty of Public Health, Faculty of Social Sciences and Humanities, Institute for Population and Social Research, Faculty of Graduate Studies, Mahidol University Health Technology Assessment (MUHTA) Graduate Program , Bangkok , Thailand.
Usa Chaikledkaewa Faculty of Pharmacy, Faculty of Medicine Ramathibodi Hospital, Faculty of Medicine Siriraj Hospital, Faculty of Public Health, Faculty of Social Sciences and Humanities, Institute for Population and Social Research, Faculty of Graduate Studies, Mahidol University Health Technology Assessment (MUHTA) Graduate Program , Bangkok , Thailand.
Due Ong Thea Faculty of Pharmacy, Faculty of Medicine Ramathibodi Hospital, Faculty of Medicine Siriraj Hospital, Faculty of Public Health, Faculty of Social Sciences and Humanities, Institute for Population and Social Research, Faculty of Graduate Studies, Mahidol University Health Technology Assessment (MUHTA) Graduate Program , Bangkok , Thailand.
Thanyanan Reungwetwattanac Division of Medical Oncology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University , Bangkok , Thailand.
Ammarin Thakkinstiana Faculty of Pharmacy, Faculty of Medicine Ramathibodi Hospital, Faculty of Medicine Siriraj Hospital, Faculty of Public Health, Faculty of Social Sciences and Humanities, Institute for Population and Social Research, Faculty of Graduate Studies, Mahidol University Health Technology Assessment (MUHTA) Graduate Program , Bangkok , Thailand.
Mahidol University · THRamathibodi Hospital · THSiriraj Hospital · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic Agents, ImmunologicalBreast NeoplasmsCardiotoxicityChemotherapy, AdjuvantDisease-Free SurvivalErb-b2 Receptor Tyrosine KinasesFemaleHumansNeoplasm StagingTrastuzumabAntineoplastic Agents, ImmunologicalERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesTrastuzumabAdjuvant chemotherapybreast cancerHER2-positivemeta-analysissystematic reviewtrastuzumab

Identifiers

PMID31287333
PMCPMC6816496
OpenAlexW2957213237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.