Evidence map›Paper›PMID 31287300›Full record

ArticleAnalytical chemistry2019

Simply Extending the Mass Range in Electron Transfer Higher Energy Collisional Dissociation Increases Confidence in N-Glycopeptide Identification.

Tomislav Čaval, Jing Zhu, Albert J R Heck

Abstract read
In one paragraph

Article in Analytical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Optimized cumate toolkit for tunable protein expression duringApplied and environmental microbiology · 2026
    Article
  3. UnderstandingJournal of the American Society for Mass Spectrometry · 2026
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  5. The protease cathepsin K can debulk the cancer glycocalyx.The Journal of biological chemistry · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. The devolution of biosimilars regulations.Nature biotechnology · 2025
    Article
  10. Glycoproteomic and proteomic analysis ofMicrobiology spectrum · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Systems-Wide Site-Specific Analysis of Glycoproteins.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tomislav ČavalBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences , University of Utrecht , Padualaan 8 , 3584 CH Utrecht , The Netherlands.
Jing ZhuBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences , University of Utrecht , Padualaan 8 , 3584 CH Utrecht , The Netherlands.
Albert J R HeckBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences , University of Utrecht , Padualaan 8 , 3584 CH Utrecht , The Netherlands.ORCID 0000-0002-2405-4404

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycopeptide-centric mass spectrometry has become a popular approach for studying protein glycosylation. However, current approaches still utilize fragmentation schemes and ranges originally optimized and intended for the analysis of typically much smaller unmodified tryptic peptides. Here, we show that by merely increasing the tandem mass spectrometry

Indexed as

ElectronsProtein Processing, Post-TranslationalAmino Acid SequenceAnimalsCarbohydrate SequenceCHO CellsCricetulusGlycopeptidesGlycosylationPeptide FragmentsPolysaccharidesProteinsTandem Mass SpectrometryGlycopeptidesPeptide FragmentsPolysaccharidesProteins

Identifiers

PMID31287300
PMCPMC6706795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.