Evidence map›Paper›PMID 31286828›Full record

Trial reportNeurorehabilitation and neural repair2019

Combining Fluoxetine and rTMS in Poststroke Motor Recovery: A Placebo-Controlled Double-Blind Randomized Phase 2 Clinical Trial.

Camila Bonin Pinto, Leon Morales-Quezada, Polyana Vulcano de Toledo Piza, Dian Zeng, Faddi Ghassan Saleh Vélez, Isadora Santos Ferreira, Pedro Henrique Lucena, Dante Duarte, Fernanda Lopes, Mirret M El-Hagrassy and 7 more

Open access · bronzeAbstract readClinical Trial, Phase IIRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neurorehabilitation and neural repair, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 7 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 7 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  6. Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery.The Cochrane database of systematic reviews · 2021
    Pooled it
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  20. Serotonergic Facilitation of Forelimb Functional Recovery in Rats with Cervical Spinal Cord Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 2 countries.

Camila Bonin Pinto1 Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-2820-8703
Leon Morales-Quezada1 Harvard Medical School, Boston, MA, USA.
Polyana Vulcano de Toledo Piza1 Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-7200-2289
Dian Zeng1 Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-5592-9584
Faddi Ghassan Saleh Vélez1 Harvard Medical School, Boston, MA, USA.
Isadora Santos Ferreira1 Harvard Medical School, Boston, MA, USA.
Pedro Henrique Lucena1 Harvard Medical School, Boston, MA, USA.
Dante Duarte1 Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-7516-5473
Fernanda Lopes1 Harvard Medical School, Boston, MA, USA.
Mirret M El-Hagrassy1 Harvard Medical School, Boston, MA, USA.
Luiz Vicente Rizzo3 Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, MA, USA.
Erica C Camargo1 Harvard Medical School, Boston, MA, USA.
David J Lin1 Harvard Medical School, Boston, MA, USA.
Nicole Mazwi1 Harvard Medical School, Boston, MA, USA.
Qing Mei Wang1 Harvard Medical School, Boston, MA, USA.
Randie Black-Schaffer1 Harvard Medical School, Boston, MA, USA.
Felipe Fregni1 Harvard Medical School, Boston, MA, USA.
Harvard University · USBrigham and Women's Hospital · US

Funding

Low frequency rTMS and fluoxetine for motor recovery after ischemic strokeR21HD079048 · NICHD · SPAULDING REHABILITATION HOSPITAL · PI FREGNI, FELIPE · 2014 to 2015
$448k
NICHD NIH HHS R21 HD079048
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Motor ActivityTranscranial Magnetic StimulationCombined Modality TherapyDouble-Blind MethodFemaleFluoxetineHumansMaleMiddle AgedParesisPyramidal TractsRecovery of FunctionSelective Serotonin Reuptake InhibitorsStrokeTreatment OutcomeUpper ExtremityFluoxetineSelective Serotonin Reuptake Inhibitorscortical excitabilityfluoxetinemotor recoveryrecovery of functionstroketranscranial magnetic stimulation

Identifiers

PMID31286828
PMCPMC6688938
OpenAlexW2958732035

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.