Evidence map›Paper›PMID 31286804›Full record

ReviewAutophagy2020

New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD.

Anaïs Larabi, Nicolas Barnich, Hang Thi Thu Nguyen

Open access · hybridAbstract readReview
In one paragraph

Review in Autophagy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 456 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
456citing papers in PubMed, 2 pooled it
47.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

456 citing papers in PubMed, 2 syntheses or guidelines pooled it, 796 citations in OpenAlex.

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  18. Oridonin-Loaded PDA@Gel@GO Nanocapsules Modulate NLRP3 and Epithelial Repair in Colitis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  19. Review
  20. Review

396 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Anaïs LarabiM2iSH, UMR 1071 Inserm, INRA USC 2018, CRNH, University of Clermont Auvergne, Clermont-Ferrand, France.
Nicolas BarnichM2iSH, UMR 1071 Inserm, INRA USC 2018, CRNH, University of Clermont Auvergne, Clermont-Ferrand, France.
Hang Thi Thu NguyenM2iSH, UMR 1071 Inserm, INRA USC 2018, CRNH, University of Clermont Auvergne, Clermont-Ferrand, France.
Inserm · FRMicrobe, Intestine, Inflammation and Host Susceptibility · FR

Funding

Therapeutics Core (Page 286)P30MH062261 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BUCH, SHILPA J., FOX, HOWARD S · 2000 to 2021
$37.7M
NIMH NIH HHS P30 MH062261
6 · The paper itself

Abstract

One of the most significant challenges of inflammatory bowel disease (IBD) research is to understand how alterations in the symbiotic relationship between the genetic composition of the host and the intestinal microbiota, under impact of specific environmental factors, lead to chronic intestinal inflammation. Genome-wide association studies, followed by functional studies, have identified a role for numerous autophagy genes in IBD, especially in Crohn disease. Studies using

Indexed as

AnimalsApoptosis Regulatory ProteinsAutophagyEndoplasmic Reticulum StressGastrointestinal MicrobiomeHumansInflammationIntestinesApoptosis Regulatory ProteinsAutophagyimmune responsesinflammatory bowel diseasesintestinal homeostasisintestinal microbiotamicrobial infection

Identifiers

PMID31286804
PMCPMC6984609
OpenAlexW2958739722

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.