ArticleJournal of clinical neurology (Seoul, Korea)2019
Association of Nutritional Status with Cognitive Stage in the Elderly Korean Population: The Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease.
Article in Journal of clinical neurology (Seoul, Korea), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Nutritional Status and Cognition in Older Adults: Modification by Apolipoprotein E ε4.Nutrients · 2026Article
- Article
- Associations Between Poor Appetite, Sarcopenia, and Cognitive Function in Community-dwelling Malaysian Older Adults.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2025Article
- Mediterranean Diet and Lifestyle in Persons with Mild to Moderate Alzheimer's Disease.Nutrients · 2024Article
- Prevention, Assessment, and Management of Malnutrition in Older Adults with Early Stages of Cognitive Disorders.Nutrients · 2024Review
- Ethnic differences in the effects of apolipoprotein E ɛ4 and vascular risk factors on accelerated brain aging.Brain communications · 2024Article
- Predicting cognitive stage transition using p-tau181, Centiloid, and other measures.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Serum neurofilament light chain level as a predictor of cognitive stage transition.Alzheimer's research & therapy · 2022Article
- Association Between Body Mass Index and Cognitive Function in Mild Cognitive Impairment Regardless of APOE ε4 Status.Dementia and neurocognitive disorders · 2022Article
- Associations between Frailty in Older Adults and Malnutrition in Rural Areas: 2019 Updated Version of the Asian Working Group for Sarcopenia.Yonsei medical journal · 2021Article
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Authors and funding
16 authors.
Funding
Abstract
background and purposeEpidemiological studies have suggested the presence of strong correlations among diet, lifestyle, and dementia onset. However, these studies have unfortunately had major limitations due to their inability to fully control the various potential confounders affecting the nutritional status. The purpose of the current study was to determine the nutritional status of participants in the Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease (KBASE) and to identify clinical risk factors for being at risk of malnutrition or being malnourished.
methodsBaseline data from 212 participants [119 cognitively unimpaired (CU), 56 with mild cognitive impairment (MCI), and 37 with dementia] included in the KBASE database were analyzed. All participants underwent a comprehensive cognitive test and MRI at baseline. The presence of malnutrition at baseline was measured by the Mini Nutritional Assessment score. We examined the cross-sectional relationships of clinical findings with nutritional status using multiple logistic regression applied to variables for which
resultsAfter adjustment for demographic, nutritional, and neuropsychological factors, participants with dementia had a significantly higher odds ratio (OR) for being at risk of malnutrition or being malnourished than CU participants [OR=5.98, 95% CI=1.20-32.97] whereas participants with MCI did not (OR=0.62, 95% CI=0.20-1.83). Cortical thinning in the at-risk/malnutrition group was observed in the left temporal area.
conclusionsDementia was found to be an independent predictor for the risk of malnutrition compared with CU participants. Our findings further suggest that cortical thinning in left temporal regions is related to the nutritional status.
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