ArticlePharmacoepidemiology and drug safety2019
Validation of mother-infant linkage using Medicaid Case ID variable within the Medicaid Analytic eXtract (MAX) database.
Article in Pharmacoepidemiology and drug safety, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Hierarchical Algorithms for Constructing Mother-Father-Infant Linkages Under Modern Privacy Constraints.Drug safety · 2026Article
- Antiemetic Combination Use During the First Trimester and Adverse Circulatory Outcomes in Newborn Infants: A Data-Mining Analysis.Drug safety · 2026Article
- Neonatal Outcome Ascertainment in Mother-Infant Paired Claims.Pharmacoepidemiology and drug safety · 2026Article
- Linking deliveries to newborns using nationwide Medicaid data.BMC medical research methodology · 2025Article
- Early School Medicaid Expansions and Health Services for Children With Parental Opioid Use Disorder.JAMA health forum · 2025Article
- A multi-level explanatory-sequential mixed-methods study of perinatal toxicology practices in New York State: Protocol.PloS one · 2025Article
- Foster Care and Health in Medicaid-Enrolled Children Experiencing Parental Opioid Use Disorder.JAMA network open · 2024Article
- Development and evaluation of an algorithm to link mothers and infants in two US commercial healthcare claims databases for pharmacoepidemiology research.BMC medical research methodology · 2023Article
- Concordance of neonatal critical condition data between secondary databases: Florida and Texas birth certificate Linkage with medicaid analytic extract.BMC medical research methodology · 2023Article
- Article
- Oral fluconazole use in the first trimester and risk of congenital malformations: population based cohort study.BMJ (Clinical research ed.) · 2020Article
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Authors and funding
8 authors.
Funding
Abstract
purposeThe state-assigned Case ID number in the Medicaid Analytic eXtract (MAX) allows for potential linkage of mothers to infants. No validation of respective linkage algorithms is available. We established and validated an algorithm within MAX that links mothers to infants and to identify factors influencing successful mother-infant linkage.
methodsWe identified all mother-infant pairs in FL and TX birth certificates records (BCR) that could be linked individually to MAX records (1999-2005 for FL and 1999-2010 for TX) based on Social Security Number (gold standard pairs). Case ID linkage performance was evaluated as the proportion of gold standard mother-infant pairs that were identified by the algorithm (sensitivity) and the proportion of algorithm defined mother-infant pairs that were correctly linked. Generalized estimating equations were used to calculate the probability for successful Case ID algorithm linkage versus non-linkage using maternal and infant characteristics.
resultsWe identified 323,160 gold standard pairs in FL BCR and MAX and 1,025,350 in TX BCR and MAX. Depending on Medicaid enrollment the algorithm sensitivity ranged from 85.51% to 87.96% in FL and 19.60% to 35.75% in TX. In both states, positive predictive value exceeded 99%, regardless of enrollment periods. Determinants for successful linkage varied across states, but suggested better results for younger mothers, minority women, and those with lower educational achievement.
conclusionsOur algorithm can correctly link liveborn infants to their mothers. The algorithm's sensitivity in identifying pairs varied across states, but PPV was consistently high. Linkage performance was associated with certain characteristics that may affect representativeness of successfully linked pairs.
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