ArticleNeurourology and urodynamics2019
Estimated kidney function in children and young adults with spina bifida: A retrospective cohort study.
Article in Neurourology and urodynamics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 25 citations in OpenAlex.
- Healthcare utilization in patients with spina bifida and bone fractures.Journal of rehabilitation medicine · 2026Observational
- Kidney Morbidity in Pediatric Patients With Spina Bifida.JAMA network open · 2026Article
- EAU-ESPU-ERN eUROGEN-ERN ITHACA-ERN ERKNet-IFSBH Guidelines on Spinal Dysraphism in Children and Adolescents: Summary of the Guideline.European urology open science · 2026Article
- Is body composition important in the context of renal function in pediatric neurogenic bladder?Pediatric nephrology (Berlin, Germany) · 2025Article
- Diagnostic Test Characteristics of Ultrasound-Based Hydronephrosis for Chronic Kidney Disease in Children and Adolescents With Myelomeningocele: Results From the UMPIRE and National Spina Bifida Patient Registry Cohort Studies.The Journal of urology · 2025Article
- Characteristics and predictors of chronic kidney disease in children with myelomeningocele: a nationwide cohort study.Pediatric nephrology (Berlin, Germany) · 2024Article
- Stratification of neurogenic bladder risk in spina bifida using the urinary peptidome.American journal of physiology. Renal physiology · 2024Article
- Article
- Impairments and comorbidities in adults with cerebral palsy and spina bifida: a meta-analysis.Frontiers in neurology · 2023Review
- Augmentation cystoplasty in children with stages III and IV chronic kidney disease secondary to neurogenic bladder.Asian journal of urology · 2022Article
- Variation in Definitions of Kidney Abnormality in Patients with Spina Bifida: A Systematic Scoping Review.The Journal of urology · 2022Article
- Are Tubular Injury Markers NGAL and KIM-1 Useful in Pediatric Neurogenic Bladder?Journal of clinical medicine · 2021Article
- Chronic kidney disease and upper tract concerns after congenital and acquired urinary tract abnormalities: considerations for transition of care in teens and young adults.World journal of urology · 2021Review
- Diagnostic Test Characteristics of Ultrasound Based Hydronephrosis in Identifying Low Kidney Function in Young Patients with Spina Bifida: A Retrospective Cohort Study.The Journal of urology · 2021Article
- Article
- Trends in Procedures to Initiate Renal Replacement Therapy among People Living with Spina Bifida.The Journal of urology · 2021Article
- Cystatin C as a biomarker of chronic kidney disease: latest developments.Expert review of molecular diagnostics · 2020Review
- Kidney Function Surveillance in the National Spina Bifida Patient Registry: A Retrospective Cohort Study.The Journal of urology · 2020Article
- [Current clinical application of glomerular filtration rate assessment methods in pediatric populations].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsReview
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
aimsCurrent estimated glomerular filtration rate (eGFR) equations may be inaccurate in patients with spina bifida (SB) because of reduced muscle mass and stature. Cross-sectional and longitudinal variability of eGFR were analyzed in these patients across multiple equations, hypothesizing greater variability in creatinine-based than cystatin-C (Cys-C)-based equations.
methodsThis retrospective cohort study included children (age, 1-17.9 years) and adults (≥18 years) with SB from 2002-2017 at a large SB clinic. Those without all data needed to calculate eGFR were excluded. Four pediatric and three adult eGFR equations were compared for cross-sectional outcomes of eGFR and elevated office blood pressures using chronic kidney disease (CKD) stage classification, and for longitudinal outcome of eGFR slope over time using covariance pattern models accounting for repeated measures.
resultsOne hundred and eighty two children and 75 adults had greater than or equal to 1 set of data measurements; 118 and 52, respectively, had greater than or equal to 2 sets. The pediatric bedside Schwartz equation had the highest median eGFR and coefficient of variation. CKD stage classification by eGFR showed large differences across equations in children, with rates of eGFR < 60 and <90 ml/min/1.73 m
conclusionsCreatinine-based equations in children with SB vary considerably from cystatin-C-containing equations in calculating both single point-in-time eGFR values and eGFR trends over time.
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