Evidence map›Paper›PMID 31286450›Full record

ArticleThe journal of physiological sciences : JPS2019

Intermittent hyperbaric oxygen exposure mobilizing peroxiredoxin 6 to prevent oxygen toxicity.

Lichao Zhang, Yanan Zhang, Zhongzhuang Wang, Yuliang Chen, Runping Li

Open access · goldAbstract read
In one paragraph

Article in The journal of physiological sciences : JPS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lichao ZhangDepartment of Pharmacy, Shanghai Hospital of Traditional Chinese Medicine, Shanghai, China.
Yanan ZhangDepartment of Diving Medicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, 200433, China.
Zhongzhuang WangDepartment of Pharmacy, Changhai Hospital, Second Military Medical University, Shanghai, China.
Yuliang ChenDepartment of Nautical and Aviation Medicine Center, Navy General Hospital, Beijing, China.
Runping LiDepartment of Diving Medicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, 200433, China. smartrpli@163.com.ORCID http://orcid.org/0000-0003-1779-7434
Second Military Medical University · CNPLA Navy General Hospital · CNShanghai Traditional Chinese Medicine Hospital · CN

Funding

National Natural Science Foundation of China No. 81471813
6 · The paper itself

Abstract

Intermittent hyperbaric oxygen exposure (IE-HBO) can protect the body against oxygen toxicity, but the underlying mechanisms are not very clear. Peroxiredoxin 6 (Prdx6) is a special endogenous antioxidative protein. We explored if the protective effects of IE-HBO are related to Prdx6. Mice were exposed to 280 kPa O

Indexed as

AnimalsAntioxidantsBrainGlutathione PeroxidaseHyperbaric OxygenationLungMaleMiceMice, Inbred C57BLOxidative StressOxygenPeroxiredoxin VIRNA, MessengerAntioxidantsGlutathione PeroxidaseOxygenPeroxiredoxin VIPrdx6 protein, mouseRNA, MessengerHyperbaric oxygenIntermittent exposureOxygen toxicityPeroxiredoxin 6Prevention

Identifiers

PMID31286450
PMCPMC10716995
OpenAlexW2956469856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.