Evidence map›Paper›PMID 31286397›Full record

Trial reportObesity surgery2019

The Effect of Intraoperative Dexmedetomidine Versus Morphine on Postoperative Morphine Requirements After Laparoscopic Bariatric Surgery.

Carine Zeeni, Marie T Aouad, Dayane Daou, Sara Naji, Samar Jabbour-Khoury, Ramzi S Alami, Bassem Y Safadi, Sahar M Siddik-Sayyid

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Obesity surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05696886 (The Effect of Intraoperative Tramadol on Postoperative Opioid Requirements After Laparoscopic Sleeve Gastrectomy for Morbid Obese Patients), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05696886 nacompletednot on this mapstarted 2021, after this paper: background citation

The Effect of Intraoperative Tramadol on Postoperative Opioid Requirements After Laparoscopic Sleeve Gastrectomy for Morbid Obese Patients (A Retrospective Multicentric Cohort Study)

TypeinterventionalSponsorMansoura UniversityRan2021 to 2022Enrolled400ConditionsPostoperative PainArmsPethidine, Tramadol with pethidine
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  3. Trial
  4. Review
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Carine ZeeniDepartment of Anesthesiology, American University of Beirut Medical Center, Beirut, Lebanon.
Marie T AouadDepartment of Anesthesiology, American University of Beirut Medical Center, Beirut, Lebanon.
Dayane DaouKeserwan Medical Center, Keserwan, Jounieh, Lebanon.
Sara NajiDepartment of Anesthesiology, American University of Beirut Medical Center, Beirut, Lebanon.
Samar Jabbour-KhouryDepartment of Anesthesiology, American University of Beirut Medical Center, Beirut, Lebanon.
Ramzi S AlamiDepartment of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
Bassem Y SafadiDepartment of Surgery, Lebanese American University, Beirut, Lebanon.
Sahar M Siddik-SayyidDepartment of Anesthesiology, American University of Beirut Medical Center, Beirut, Lebanon. ss01@aub.edu.lb.ORCID http://orcid.org/0000-0002-1135-0925
American University of Beirut Medical Center · LBLebanese American University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDexmedetomidine is an α

methodsSixty morbidly obese patients (BMI > 40 kg m

resultsThere was no significant difference in morphine consumption in the PACU (group D 12.2 ± 5.44 mg, group M 13.28 ± 6.64 mg, P = 0.54) or at 24 h (group D 40.67 ± 24.78 mg, group M 43.28 ± 27.79 mg, P = 0.75); when accounting for intraoperative morphine given group M had significantly higher morphine consumption when compared to group D (23.48 ± 6.22 mg vs. 12.22 ± 5.54 mg, respectively, P < 0.01). Group D patients had more cardiovascular stability.

conclusionsDexmedetomidine given prior to end of laparoscopic sleeve gastrectomy provides the same level of postoperative analgesia as morphine with better hemodynamic profile.

Indexed as

AdolescentAdultAnalgesicsAnalgesics, Non-NarcoticAnalgesics, OpioidAnesthesia Recovery PeriodBariatric SurgeryDexmedetomidineDose-Response Relationship, DrugDouble-Blind MethodFemaleHumansHypnotics and SedativesIntraoperative CareLaparoscopyLebanonAnalgesicsAnalgesics, Non-NarcoticAnalgesics, OpioidDexmedetomidineHypnotics and SedativesMorphineBariatric surgeryDexmedetomidineMorphineObesityPostoperative pain

Identifiers

PMID31286397
OpenAlexW2962312932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.