Evidence map›Paper›PMID 31286387›Full record

Trial reportJournal of cancer survivorship : research and practice2019

Long-term effectiveness and cost-effectiveness of an 18-week supervised exercise program in patients treated with autologous stem cell transplantation: results from the EXIST study.

Johanna M van Dongen, Saskia Persoon, Gabrielle Jongeneel, Judith E Bosmans, Marie José Kersten, Johannes Brug, Frans Nollet, Mai J M Chinapaw, Laurien M Buffart

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cancer survivorship : research and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06134297 (Adherence, Feasibility, Clinical Evolution Therapeutic Efficacy of Three Different Muscle Overload Models Used for Physical Rehabilitation of Patients Undergoing Bone Marrow Transplantation), which is not on this map. Cited by 26 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06134297 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Adherence, Feasibility, Clinical Evolution Therapeutic Efficacy of Three Different Muscle Overload Models Used for Physical Rehabilitation of Patients Undergoing Bone Marrow Transplantation: a Randomized Clinical Trial

TypeinterventionalSponsorFederal University of Health Science of Porto AlegreRan2022 to 2024Enrolled93ConditionsStem Cell TransplantationArmsCycle ergometer, Strength Training - elastic band and shin guards, Cycle ergometer, elastic band and shin guards
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Pooled it
  2. Management of Fatigue in Adult Survivors of Cancer: ASCO-Society for Integrative Oncology Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Guideline
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  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. To what extent does the use of crosswalks instead of EQ-5D value sets impact reimbursement decisions?: a simulation study.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Article
  18. Article
  19. Physical Activity in Multiple Myeloma: A Review of the Current Literature.Journal of the advanced practitioner in oncology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Johanna M van DongenVrije Universiteit Amsterdam, Department of Health Sciences, Faculty of Science, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
Saskia PersoonAmsterdam UMC, University of Amsterdam, Department of Rehabilitation, Amsterdam Movement Sciences, Amsterdam, The Netherlands.
Gabrielle JongeneelAmsterdam UMC, Vrije Universiteit Amsterdam, Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, De Boelelaan 1089a, 1018HV, Amsterdam, The Netherlands.
Judith E BosmansVrije Universiteit Amsterdam, Department of Health Sciences, Faculty of Science, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
Marie José KerstenAmsterdam UMC, University of Amsterdam, Department of Haematology, Amsterdam, The Netherlands.
Johannes BrugNational Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Frans NolletAmsterdam UMC, University of Amsterdam, Department of Rehabilitation, Amsterdam Movement Sciences, Amsterdam, The Netherlands.
Mai J M ChinapawAmsterdam UMC, Vrije Universiteit Amsterdam, Department of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
Laurien M BuffartAmsterdam UMC, Vrije Universiteit Amsterdam, Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, De Boelelaan 1089a, 1018HV, Amsterdam, The Netherlands. l.buffart@vumc.nl.

Funding

KWF Kankerbestrijding ALPE 2009-4620
6 · The paper itself

Abstract

purposeTo evaluate the long-term effectiveness and cost-effectiveness of a supervised 18-week high-intensity exercise program compared with usual care in patients treated with autologous stem cell transplantation.

methodsOne hundred nine patients were randomly assigned to the exercise intervention (n = 54) or the usual care control group (n = 55). Data on cardiorespiratory fitness (VO

resultsAt T2, no statistically significant differences were found between the intervention and control group for VO

conclusionWe found no evidence for the exercise intervention being effective on physical fitness and fatigue, nor cost-effective from a societal perspective.

trial registrationThe study was prospectively registered on 27 May 2010 at the Netherlands Trial Register ( NTR2341 ). IMPLICATIONS FOR CANCER SURVIVORS: The current exercise intervention should not be recommended to patients recently treated with autologous stem cell transplantation.

Indexed as

Cancer SurvivorsHematopoietic Stem Cell TransplantationAdultCardiorespiratory FitnessCost-Benefit AnalysisExercise TherapyFatigueFemaleFollow-Up StudiesHand StrengthHematologic NeoplasmsHumansMaleMiddle AgedNetherlandsPhysical FitnessCost-effectivenessExercise interventionLong-term effectivenessLymphomaMultiple myeloma

Identifiers

PMID31286387
PMCPMC6677707

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.