Evidence map›Paper›PMID 31286305›Full record

ArticleNeurosurgical review2020

Management of hydrocephalus after resection of posterior fossa lesions in pediatric and adult patients-predictors for development of hydrocephalus.

Sae-Yeon Won, Daniel Dubinski, Bedjan Behmanesh, Joshua D Bernstock, Volker Seifert, Juergen Konczalla, Stephanie Tritt, Christian Senft, Florian Gessler

Abstract read
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In one paragraph

Article in Neurosurgical review, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
  5. Observational
  6. Article
  7. Article
  8. ETV for fourth ventricle outlet obstruction (FVOO) in the long-term period following pediatric posterior fossa tumor resection.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
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  15. Pediatric-Like Brain Tumors in Adults.Advances and technical standards in neurosurgery · 2024
    Review
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Sae-Yeon WonDepartment of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany. sae-yeon.won@kgu.de.ORCID http://orcid.org/0000-0001-6585-5403
Daniel DubinskiDepartment of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.
Bedjan BehmaneshDepartment of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.
Joshua D BernstockMedical Scientist Training Program, University of Alabama at Birmingham, Birmingham, AL, USA.
Volker SeifertDepartment of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.
Juergen KonczallaDepartment of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.
Stephanie TrittDepartment of Radiology, Helios Dr. Horst Schmidt Hospital, Wiesbaden, Germany.
Christian SenftDepartment of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.
Florian GesslerDepartment of Neurosurgery, University Hospital, Goethe-University, Frankfurt am Main, Germany.
Goethe University Frankfurt · DEUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The surgical management of hydrocephalus in patients with posterior fossa lesions (PFL) is critical for optimal patient outcome(s). Accordingly, it is prudent to identify patients in need of aggressive surgical intervention (i.e., ventriculoperitoneal [VP] shunting). To analyze prevalence of, and risk factors associated with, the development of post-operative hydrocephalus in both pediatrics and adults. A retrospective institutional analysis and review of patient records in those who had undergone PFL surgery was performed. In so doing, the authors identified patients that went on to develop post-operative hydrocephalus. The study included pediatric and adult patients treated between 2009 and 2017. Fifteen of 40 pediatric (37.5%) and 18 of 262 adult (6.9%) patients developed hydrocephalus after PFL surgery. The most common tumor entity in pediatrics was medulloblastoma (34%), astrocytoma (24.4%), and pilocytic astrocytoma (22%), whereas in adults, metastasis (29.5%), meningioma (22%), and acoustic neuroma (17.8%) were most common. Young age ≤ 2 years, medulloblastoma (OR 13.9), and brain stem compression (OR 5.4) were confirmed as independent predictors for hydrocephalus in pediatrics and pilocytic astrocytoma (OR 15.4) and pre-operative hydrocephalus (OR 3.6) in adults, respectively. All patients received VP shunts for hydrocephalus management and the mean follow-up was 29.5 months in pediatrics vs 19.2 months in adults. Overall complication rates related to VP shunts were 33.3% in pediatrics and 16.7% in adults, respectively. Shunt dependency and associated complications in pediatrics were noted to be higher than in adults. Given the identification of predictors for hydrocephalus, it is authors' contention that certain patients with those predictors may ultimately benefit from an alternative treatment regimen (e.g., pre-operative interventions) prior to PFT surgery.

Indexed as

AdolescentAdultAgedAge FactorsBrain NeoplasmsCerebrospinal Fluid ShuntsChildChild, PreschoolCranial Fossa, PosteriorFollow-Up StudiesHumansHydrocephalusInfantMiddle AgedNeurosurgical ProceduresPostoperative ComplicationsAdultsHydrocephalusPediatricsPosterior fossa tumorPredictorsShunt dependency

Identifiers

PMID31286305
OpenAlexW2956180212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.