Evidence map›Paper›PMID 31286266›Full record

ReviewWorld journal of microbiology & biotechnology2019

Regulation and metabolic engineering strategies for permeases of Saccharomyces cerevisiae.

Peng Zhang, Qian Chen, Guiming Fu, Linglin Xia, Xing Hu

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Peng ZhangState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, 330047, China.
Qian ChenState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, 330047, China.
Guiming FuState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, 330047, China.
Linglin XiaDepartment of Software, Nanchang University, Nanchang, 330047, China.
Xing HuState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, 330047, China. hx0726@ncu.edu.cn.ORCID http://orcid.org/0000-0002-4590-3671
Nanchang University · CN

Funding

National Natural Science Foundation of China 31801470Undergraduate Training Program for Innovation and Entrepreneurship of Nanchang University 2018303Undergraduate Training Program for Innovation and Entrepreneurship of Nanchang University 20190402112
6 · The paper itself

Abstract

Microorganisms have evolved permeases to incorporate various essential nutrients and exclude harmful products, which assists in adaptation to different environmental conditions for survival. As permeases are directly involved in the utilization of and regulatory response to nutrient sources, metabolic engineering of microbial permeases can predictably influence nutrient metabolism and regulation. In this mini-review, we have summarized the mechanisms underlying the general regulation of permeases, and the current advancements and future prospects of metabolic engineering strategies targeting the permeases in Saccharomyces cerevisiae. The different types of permeases and their regulatory mechanisms have been discussed. Furthermore, methods for metabolic engineering of permeases have been highlighted. Understanding the mechanisms via which permeases are meticulously regulated and engineered will not only facilitate research on regulation of global nutrition and yeast metabolic engineering, but can also provide important insights for future studies on the synthesis of valuable products and elimination of harmful substances in S. cerevisiae.

Indexed as

Biological TransportCarbonGlucoseMembrane Transport ProteinsMetabolic EngineeringNitrogenSaccharomyces cerevisiaeCarbonGlucoseMembrane Transport ProteinsNitrogenAmino acids transportGlucose transportMetabolic engineering strategiesTransporter engineering

Identifiers

PMID31286266
OpenAlexW2957489480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.