ArticleClinical oral investigations2020
Clinical and histological reaction of periodontal tissues to subgingival resin composite restorations.
Article in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06497231 (Clinical and Periodontal Evaluation of Deep Marginal Elevation for Proximal Carious Lesions Restored with Bioactive Giomer Versus Nanohybrid Resin Composite), which is not on this map. Cited by 49 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical and Periodontal Evaluation of Deep Marginal Elevation for Proximal Carious Lesions Restored with Bioactive Giomer Versus Nanohybrid Resin Composite: Two Years Randomized Trial
Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Enhancing subgingival margin restoration: a comprehensive review and meta-analysis of deep margin elevation's impact on microleakage.Evidence-based dentistry · 2024Pooled it
- Relationship between Deep Marginal Elevation and Periodontal Parameters: A Systematic Review.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Effect of deep margin elevation with different injectable materials on performance of CAD/CAM-Fabricated nanoceramic-resin onlays: 3-year randomized clinical trial.Clinical oral investigations · 2026Trial
- Periodontal status of indirect resin composite restorations with proximal box elevation: 3-year clinical results.Clinical oral investigations · 2025Trial
- Different Designs of Deep Marginal Elevation and Its Influence on Fracture Resistance of Teeth with Monolith Zirconia Full-Contour Crowns.Medicina (Kaunas, Lithuania) · 2023Trial
- Effect of deep margin elevation with different base materials on periodontal health in a clinical study.Scientific reports · 2026Article
- Deep Margin Elevation and Lithium Disilicate Overlay Restoration of an Endodontically Treated Molar: A Case Report.Cureus · 2026Article
- Article
- Effect of deep marginal elevation with different intermediate materials on the fracture resistance of direct and indirect final composite restorations: an in vitro study.Scientific reports · 2026Article
- The Perio-Resto Interface: In Vitro Comparison of Two Deep Margin Elevation Techniques on Surface Roughness, Marginal Adaptation and Material Integrity.Dentistry journal · 2026Article
- Developing anti-inflammatory mineral trioxide aggregate as dental implant crown cement to reduce peri-implantitis incidence.Journal of dental sciences · 2026Article
- The Biocompatibility and Cellular Response of Geristore in Comparison With Different Glass Ionomer Materials on Human Gingival Fibroblast Cells: A Comparative Study on Deep Marginal Elevation.International journal of biomaterials · 2026Article
- Comparative evaluation of cervical microleakage in class II composite restorations using different liner and placement techniques: AnJournal of conservative dentistry and endodontics · 2025Article
- Restorative and Periodontal Outcomes of Deep Margin Elevation in Posterior Teeth: A Systematic Review.Cureus · 2025Review
- Evaluation of Salivary GAPDH as a Predictor Biomarker for Periodontitis.International journal of molecular sciences · 2025Article
- Activation of Inflammatory and Apoptosis Pathways on Human Gingival Fibroblasts Exposed to Dental Resin Composites.Polymers · 2025Article
- [Restorative strategies for complex crown-root fractures in the esthetic zone: a risk assessment based on the restoration-tooth-periodontium interface].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025Article
- Influence of deep marginal elevation on the marginal adaptation and fracture resistance of zirconia endocrowns constructed on endodontically treated premolar teeth: in vitro study.The Saudi dental journal · 2025Article
- Article
- The Impact of Nonsurgical Periodontal Therapy on the Salivary Proteome: A Pilot Study.International journal of dentistry · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare the clinical and histological response of supracrestal periodontal tissues to subgingival composite restorations versus natural root surfaces MATERIAL AND
methodsIn 29 subjects with a single tooth requiring subgingival restorations, a deep margin elevation (DME) procedure with composite resin was applied. Full-mouth plaque score (FMPS), full-mouth bleeding score (FMBS), and focal probing depth (PD) were measured at baseline, before DME, and after 3 months. The distance between the coronal marked (CM) point to the apical margin of the composite reconstruction (AMR), at baseline, and to the tip of the periodontal probe inserted to reach the bottom of the sulcus (APP), 3 months later, was measured. An all-around secondary flap, harvested to ensure the subsequent single-crown prosthetic rehabilitation was histologically processed. The histological inflammation degree was evaluated in areas of gingival tissues adjacent to the composite (group B) and adjacent to the natural surface of each single tooth (group A).
resultsSignificant FMPS, FMBS, and PD decreases were observed (p < 0.05). CM-AMR and CM-APP were significantly different (p < 0.05), suggesting an attachment gain after 3-months. The inflammation level of gingival tissue was similar in groups A and B (p > 0.05).
conclusionsFor the first time, this topic was clinically and histologically studied in humans. Subgingival restorations resulted compatible with gingival health, with levels similar to that of untreated root surfaces. CLINICAL RELEVANCE: Deep margin elevation procedure produces favorable clinical and histological outcomes allowing a routine utilization in reconstructive dentistry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.