Trial reportClinical oral investigations2020
Dimensional changes following alveolar ridge preservation in the posterior area using bovine-derived xenografts and collagen membrane compared to spontaneous healing: a 6-month randomized controlled clinical trial.
Trial report in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 6 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Allograft versus xenograft for alveolar ridge preservation in non-molar extraction sockets: a systematic review and meta-analysis of randomized controlled trials.Clinical oral investigations · 2026Pooled it
- Alveolar ridge preservation versus unassisted socket healing following tooth extraction: a systematic review of controlled clinical studies and meta-analysis of randomised trials.Oral and maxillofacial surgery · 2026Pooled it
- Autologous platelet concentrates in alveolar ridge preservation: A systematic review with meta-analyses.Periodontology 2000 · 2025Pooled it
- Bone envelope for implant placement after alveolar ridge preservation: a systematic review and meta-analysis.International journal of implant dentistry · 2022Pooled it
- Dimensional and histomorphometric evaluation of biomaterials used for alveolar ridge preservation: a systematic review and network meta-analysis.Clinical oral investigations · 2022Pooled it
- Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development.The Cochrane database of systematic reviews · 2021Pooled it
- Comparative efficacy of modified versus standard deproteinized bovine bone mineral for compromised socket preservation: a randomized controlled trial.BMC oral health · 2026Trial
- Effect of platelet-rich fibrin on microperfusion during early socket healing: a randomized controlled clinical trial.Clinical oral investigations · 2025Trial
- Alveolar Ridge Preservation Using a Collagenated Xenograft: A Randomized Clinical Trial.International dental journal · 2025Trial
- Analysis of Soft Tissue Healing Over Socket Orifice Sealed with Platelet-Rich Fibrin Membrane.European journal of dentistry · 2026Article
- Effectiveness of β-TriCalcium Phosphate for Alveolar Ridge Preservation: A Systematic Review.Journal of functional biomaterials · 2026Review
- The Microbial Diversity and Biofilm Characteristics of d-PTFE Membranes Used for Socket Preservation: A Randomized Controlled Clinical Trial.Journal of functional biomaterials · 2025Article
- The Long-Term Esthetic and Radiographic Outcome of Implants Placed in the Anterior Maxilla after Ridge Preservation, Combining Bovine Xenograft with Collagen Matrix.Dentistry journal · 2024Article
- Efficacy of Alveolar Ridge Preservation in Periodontally Compromised Molar Extraction Sites: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Effectiveness of a collagen matrix seal and xenograft in alveolar ridge preservation: an experimental study in dogs.Scientific reports · 2024Article
- Alveolar Ridge Preservation with a Novel Cross-Linked Collagen Sponge: Histological Findings from a Case Report.Journal of clinical medicine · 2023Article
- Biomaterials for Alveolar Ridge Preservation as a Preoperative Procedure for Implant Treatment: History and Current Evidence.Bioengineering (Basel, Switzerland) · 2023Review
- A comparison between anorganic bone and collagen-preserving bone xenografts for alveolar ridge preservation: systematic review and future perspectives.Maxillofacial plastic and reconstructive surgery · 2022Review
- A Retrospective Digital Analysis of Contour Changing after Tooth Extraction with or without Using Less Traumatic Surgical Procedures.Journal of clinical medicine · 2022Article
- Assessment of Accessory Canals and Foramina in the Mandibular Arch Using Cone-Beam Computed Tomography and a New Classification for Mandibular Accessory Canals.BioMed research international · 2022Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess dimensional changes following alveolar ridge preservation using bovine-derived xenograft with 10% collagen and collagen membrane compared to ridge preservation by means of bovine-derived xenograft particles and collagen membrane or spontaneous healing in posterior sites. MATERIALS AND
methodsForty subjects with 40 posterior teeth or roots candidate to extraction and presenting integrity of alveolar bone walls were randomly allocated into three groups. Patients of test group were treated by ridge preservation technique using bovine-derived xenograft with 10% collagen and collagen membrane; patients of control group 1 were treated by means of bovine-derived xenograft particles and collagen membrane while in patients of control group 2, no grafting was performed. Changes in vertical and horizontal bone dimensions were compared at baseline and after 6-month observation time.
resultsStatistically significant differences between baseline and 6 month were observed in all groups in terms of vertical and horizontal bone resorption (p < 0.001), except for vertical resorption in control group 2. After 6-month intergroup comparisons showed not statistically significant changes between test and control groups in terms of alveolar bone changes (p > 0.05).
conclusionsWithin the limits of this study, the sites grafted using bovine-derived xenograft with 10% collagen in combination with a collagen membrane showed no statistical differences in terms of vertical and horizontal bone resorption compared to control groups. CLINICAL RELEVANCE: Ridge preservation in posterior area failed to show clinically relevant benefits in sites presenting integrity of alveolar bone walls and adequate buccal bone wall thickness.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.