ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2019
Usefulness of dynamic contrast-enhanced magnetic resonance images for distinguishing between pyogenic spondylitis and tuberculous spondylitis.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Recommendations of the International Consensus Meeting (ICM) 2025 on Spinal Infections: Part B Tubercular Spondylodiscitis.Global spine journal · 2026Article
- Differentiating Tuberculous and Pyogenic Spondylodiscitis: Part II: MRI/CT Features, Prediction Models, and the Role of PET/CT-A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Deep learning radiomics model based on contrast-enhanced MRI for distinguishing between tuberculous spondylitis and pyogenic spondylitis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Imaging update in spinal tuberculosis.Journal of clinical orthopaedics and trauma · 2022Review
- Analysis of the diagnostic efficacy of the QuantiFERON-TB Gold In-Tube assay for preoperative differential diagnosis of spinal tuberculosis.Frontiers in cellular and infection microbiology · 2022Article
- Differentiating tubercular from pyogenic causes of spine involvement on Magnetic Resonance Imaging.Le infezioni in medicina · 2022Article
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeDynamic contrast-enhanced (DCE)-MRI is used for examining the features of malignant tumours in radiology, and we can obtain more information in terms of the diffusion of the media over the course of time. The purpose of this study was to clarify the usefulness of DCE-MRI for distinguishing pyogenic spondylitis (PS) and tuberculous spondylitis (TB).
methodsForty-five consecutive patients diagnosed with PS (68.6 ± 11.1 years old, males 30 and females 15) and 14 with TB (73.9 ± 9.1 years old, males 6 and females 8) were involved. DCE-MRI consisted of serial six sagittal images which were taken every 20 s after intravenous gadolinium administration. Degree of enhancement, presence of epidural abscess, presence of necrosis in vertebra, presence of enhancement in disc lesion, pattern of diffusion, and maximum contrast index were examined and compared between PS and TB.
resultsDegree of enhancement, percentage of epidural abscess, and percentage of necrosis in vertebra were 2.1 ± 0.5 and 1.8 ± 0.8, 60.7% and 100%, 50.0% and 66.7% for PS and TB, respectively, without statistical difference. Maximum contrast index, percentage of the diffusion pattern from the disc, and percentage of enhanced disc were 108.1 ± 22.3 and 78.2 ± 35.6 s, 89.3% and 0%, and 53.6% and 0% for PS and TB, respectively, with statistical significance.
conclusionsThis study indicated that longer maximum contrast index, higher likelihood of diffusion pattern from the disc, and higher likelihood of enhanced disc are more specific to PS than TB. This less invasive imaging technique is useful for more accurate diagnosis of PS and TB. These slides can be retrieved under Electronic Supplementary Material.
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