Evidence map›Paper›PMID 31286107›Full record

ArticleJournal of the Endocrine Society2019

Fatty Liver Has Stronger Association With Insulin Resistance Than Visceral Fat Accumulation in Nonobese Japanese Men.

Satoshi Kadowaki, Yoshifumi Tamura, Yuki Someya, Kageumi Takeno, Hideyoshi Kaga, Daisuke Sugimoto, Saori Kakehi, Takashi Funayama, Yasuhiko Furukawa, Ruriko Suzuki and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Crosstalk between Metabolic Disorders and Immune Cells.International journal of molecular sciences · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Satoshi KadowakiDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yoshifumi TamuraDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID 0000-0003-0943-0712
Yuki SomeyaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kageumi TakenoDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hideyoshi KagaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Daisuke SugimotoDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Saori KakehiDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Takashi FunayamaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yasuhiko FurukawaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Ruriko SuzukiDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Miho Nishitani-YokoyamaDepartment of Cardiology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kazunori ShimadaSportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hiroyuki DaidaSportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Shigeki AokiSportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Akio KanazawaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Ryuzo KawamoriDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hirotaka WatadaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Juntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextAsians have a high prevalence of insulin resistance, even in the nonobese state. Whereas both visceral fat accumulation (VFA) and fatty liver (FL) have been shown to be associated with insulin resistance, it is still unclear which is a better marker to predict insulin resistance in nonobese Asians.

objectiveThe aim of this study was to investigate the relation between VFA or FL and insulin resistance in nondiabetic nonobese Japanese men who do not have diabetes. DESIGN AND

participantsWe studied 87 nonobese (body mass index <25 kg/m

resultsSubjects in the FL only and VFA plus FL groups had insulin resistance in adipose tissue and muscle, as well as relatively lower hepatic insulin sensitivity. The specific insulin sensitivities in these organs were comparable in the VFA only and control groups.

conclusionsIn nonobese Japanese men without diabetes, subjects with FL only or VFA plus FL but not VFA only had insulin resistance, suggesting that FL may be a more useful clinical marker than VFA to predict insulin resistance in nonobese Japanese men without diabetes.

Indexed as

ectopic fatfatty livernonobesevisceral fat

Identifiers

PMID31286107
PMCPMC6608549
OpenAlexW2945630654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.