Evidence map›Paper›PMID 31286105›Full record

ArticleJournal of the Endocrine Society2019

Lateralizing Asymmetry of Adrenal Imaging and Adrenal Vein Sampling in Patients With Primary Aldosteronism.

Norio Wada, Yui Shibayama, Takashi Yoneda, Takuyuki Katabami, Isao Kurihara, Mika Tsuiki, Takamasa Ichijo, Yoshihiro Ogawa, Junji Kawashima, Masakatsu Sone and 10 more

Abstract read
In one paragraph

Article in Journal of the Endocrine Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Asymmetric Adrenals: Sexual Dimorphism of Adrenal Tumors.The Journal of clinical endocrinology and metabolism · 2024
    Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Norio WadaDepartment of Diabetes and Endocrinology, Sapporo City General Hospital, Sapporo, Japan.ORCID 0000-0001-9796-4890
Yui ShibayamaDepartment of Diabetes and Endocrinology, Sapporo City General Hospital, Sapporo, Japan.
Takashi YonedaDepartment of Health Promotion and Medicine of the Future, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Takuyuki KatabamiDivision of Metabolism and Endocrinology, Department of Internal Medicine, St Marianna University School of Medicine Yokohama City Seibu Hospital, Yokohama, Japan.
Isao KuriharaDivision of Endocrinology, Metabolism and Nephrology, Keio University School of Medicine, Tokyo, Japan.
Mika TsuikiMetabolism and Hypertension, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Takamasa IchijoDepartment of Diabetes and Endocrinology, Saiseikai Yokohamashi Tobu Hospital, Yokohama, Japan.
Yoshihiro OgawaDepartment of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Junji KawashimaDepartment of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Masakatsu SoneDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takanobu YoshimotoDepartment of Molecular Endocrinology and Metabolism, Graduate School of Medicine, Tokyo Medical Dental University, Tokyo, Japan.
Yuichi MatsudaDepartment of Cardiology, Sanda City Hospital, Sanda, Japan.
Megumi FujitaDivision of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.
Hiroki KobayashiDivision of Nephrology, Hypertension, and Endocrinology, Nihon University School of Medicine, Tokyo, Japan.
Kouichi TamuraDepartment of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Kohei KamemuraDepartment of Cardiology, Shinko Hospital, Kobe, Japan.
Michio OtsukiDepartment of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
Shintaro OkamuraDepartment of Endocrinology, Tenriyorozu Hospital, Tenri, Japan.
Mitsuhide NaruseMetabolism and Hypertension, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
JPAS/JRAS Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextIn patients with primary aldosteronism (PA), it remains unclear whether aldosterone-producing adenomas are likely to develop in the left or right adrenal gland.

objectiveTo investigate left-right differences of PA laterality diagnoses via CT imaging and adrenal vein sampling (AVS).

designRetrospective, observational study. PATIENTS: From the Japan Primary Aldosteronism Study, 1493 patients with PA were enrolled who underwent CT and ACTH-stimulated AVS. MEASUREMENTS: Left or right adrenal nodular lesion distribution and laterality observed on CT scans and from AVS were noted.

resultsBoth on CT scans and AVS, unilateral results were observed more frequently on the left side than on the right side (25.1% vs 15.4% and 17.3% vs 13.5%, respectively;

conclusionThese results suggest aldosterone-producing adenomas and nonfunctioning tumors are more likely to develop on the left side in patients with PA and that misdiagnosis of CT-based lateralization may occur more frequently on the left side.

Indexed as

adrenal vein 87 samplingcomputed tomographyhypertensionleft-right differenceprimary aldosteronism

Identifiers

PMID31286105
PMCPMC6608550

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.