ArticleOptica2019
Thermal Memory Based Photoacoustic Imaging of Temperature.
Article in Optica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Listening to Immunotherapy - Ultrasound and Photoacoustic Imaging Strategies to Guide and Enhance Cancer Treatments.Molecular imaging and biology · 2026Review
- Noninvasive detection and prediction method for temperature inJournal of biomedical optics · 2026Article
- Direct-Necrosis-Monitoring-Based Adaptive Model Predictive Control for Ablation Therapy Including Patient-Specific Residual Heat Management.Annals of biomedical engineering · 2026Article
- Artifacts in photoacoustic imaging: Origins and mitigations.Photoacoustics · 2025Article
- Advancing precision photothermal therapy by integrating armored gold nanostars with real-time photoacoustic thermometry and imaging.Science advances · 2025Article
- Image-Based Monitoring of Thermal Ablation.Bioengineering (Basel, Switzerland) · 2025Review
- Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Perspectives on endoscopic functional photoacoustic microscopy.Applied physics letters · 2024Article
- The State-of-the-Art and Perspectives of Laser Ablation for Tumor Treatment.Cyborg and bionic systems (Washington, D.C.) · 2024Article
- Noninvasive measurement of local temperature using ultrasound-switchable fluorescence.Biomedical optics express · 2023Article
- Multiscale photoacoustic tomography using reversibly switchable thermochromics.Journal of biomedical optics · 2023Article
- Niche preclinical and clinical applications of photoacoustic imaging with endogenous contrast.Photoacoustics · 2023Review
- Real-time assessment of high-intensity focused ultrasound heating and cavitation with hybrid optoacoustic ultrasound imaging.Photoacoustics · 2023Article
- In vivo photothermal therapy monitored by multi-position calibrated photoacoustic thermometer.Photoacoustics · 2023Article
- Absolute Grüneisen parameter measurement in deep tissue based on X-ray-induced acoustic computed tomography.Biomedical optics express · 2023Article
- Optoacoustic Sensing of Surfactant Crude Oil in Thermal Relaxation and Nonlinear Regimes.Sensors (Basel, Switzerland) · 2021Article
- Photoacoustic computed tomography of mechanical HIFU-induced vascular injury.Biomedical optics express · 2021Article
- Nonlinear mechanisms in photoacoustics-Powerful tools in photoacoustic imaging.Photoacoustics · 2021Review
- Internal-Illumination Photoacoustic Tomography Enhanced by a Graded-Scattering Fiber Diffuser.IEEE transactions on medical imaging · 2021Article
- Hybrid deep learning network for vascular segmentation in photoacoustic imaging.Biomedical optics express · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Temperature mapping is essential in many biomedical studies and interventions to precisely control the tissue's thermal conditions for optimal treatment efficiency and minimal side effects. Based on the Grüneisen parameter's temperature dependence, photoacoustic (PA) imaging can provide relative temperature measurement, but it has been traditionally challenging to measure absolute temperatures without knowing the baseline temperature, especially in deep tissues with unknown optical and acoustic properties. Here, we report a new thermal-energy-memory-based photoacoustic thermometry (TEMPT). By illuminating the tissue with a burst of nanosecond laser pulses, TEMPT exploits the temperature dependence of the thermal energy lingering, which is probed by the corresponding PA signals acquired within the thermal confinement. A self-normalized ratiometric measurement cancels out temperature-irrelevant quantities and estimates the Grüneisen parameter. The temperature can then be evaluated, given the tissue's temperature-dependent Grüneisen parameter, mass density, and specific heat capacity. Unlike the conventional PA thermometry, TEMPT does not require the knowledge of tissue's baseline temperature, nor the optical properties. We have developed a mathematical model to describe the temperature dependence in TEMPT. We have demonstrated the feasibility of the temperature evaluation on tissue phantoms at 1.5 cm depth within a clinically relevant temperature range. Finally, as proof-of-concept, we applied TEMPT for temperature mapping during focused ultrasound treatment in mice
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.