Evidence map›Paper›PMID 31285948›Full record

ArticleAmerican journal of cancer research2019

Stabilization of PTGES by deubiquitinase USP9X promotes metastatic features of lung cancer via PGE

Tong Wang, Bo Jing, Beibei Sun, Yueling Liao, Hongyong Song, Dongliang Xu, Wenzheng Guo, Kaimi Li, Min Hu, Shuli Liu and 5 more

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. EFNA4-enhanced deubiquitination of SLC7A11 inhibits ferroptosis in hepatocellular carcinoma.Apoptosis : an international journal on programmed cell death · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. PTGES/PGEOncogene · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Tong WangKey Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Bo JingKey Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Beibei SunTranslational Medical Research Center, Shanghai Chest Hospital, Shanghai Jiao Tong University Shanghai, China.
Yueling LiaoKey Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Hongyong SongKey Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Dongliang XuKey Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Wenzheng GuoKey Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Kaimi LiKey Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Min HuKey Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Shuli LiuDepartment of Oral and Maxillofacial-Head and Neck Oncology, The Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Jing LingDepartment of Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Yanbin KuangDepartment of Respiratory Medicine, The Second Affiliated Hospital, Dalian Medical University Dalian, China.
Yao FengDepartment of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University Shanghai, China.
Binhua P ZhouDepartment of Molecular and Cellular Biochemistry, Markey Cancer Center, University of Kentucky College of Medicine Lexington, KY, USA.
Jiong DengKey Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Shanghai Jiao Tong University School of Medicine Shanghai, China.
Shanghai Jiao Tong University · CNShanghai Chest Hospital · CNDalian Medical University · CNMarkey Cancer Center · USMinistry of Education · THShanghai Ninth People's Hospital · CN

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Bernard Mark Evers · 2013 to 2026
$38.3M
NCI NIH HHS P30 CA177558
6 · The paper itself

Abstract

Early metastasis and local recurrence are the major causes of mortality and poor prognosis of non-small cell lung cancer (NSCLC). However, the underlying mechanisms of these processes are poorly understood. In this study, we aimed to investigate the roles of the PTGES/PGE

Indexed as

metastasisnon-small cell lung cancerPGE2PTGESUSP9X

Identifiers

PMID31285948
PMCPMC6610053
OpenAlexW2984431396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.