ArticleJournal of thoracic disease2019
Prognosis of patients with acute respiratory failure and prolonged intensive care unit stay.
Article in Journal of thoracic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Long-term lung function recovery after ECMO versus non-ECMO management in acute respiratory failure: a systematic review and meta-analysis.BMC pulmonary medicine · 2024Pooled it
- Surface electromyography signal processing and evaluation on respiratory muscles of critically ill patients: A systematic review.PloS one · 2023Pooled it
- Impact of ICU Length of Stay and Illness Severity on Rehabilitation Progress and Functional Recovery: A Secondary Analysis of the Japanese Rehabilitation and Risk Factors on the Post-Intensive Care Syndrome (J-RELIFE) Prospective Registry.Critical care explorations · 2025Article
- Prognostic Factors Affecting Mortality Among Patients Admitted to the Intensive Care Unit with Acute Hypoxemic Respiratory Failure.Diagnostics (Basel, Switzerland) · 2025Article
- Diaphragmatic ultrasound: approach, emerging evidence, and future perspectives in non-ICU patients.Internal and emergency medicine · 2025Review
- Systemic Immune Inflammation Index (SII) and Prognostic Nutritional Index (PNI) Associated with Prolonged Intensive Care Unit (ICU) Stay in Patients with Pneumonia Complicated with Respiratory Failure.International journal of general medicine · 2025Article
- HIRA: Heart Rate Interval based Rapid Alert score to characterize autonomic dysfunction among patients with sepsis-related acute respiratory failure (ARF).Physiological measurement · 2023Article
- Predictors of Outcome in Patients with Pulmonary Hypertension Undergoing Mitral and Tricuspid Valve Surgery.Medicina (Kaunas, Lithuania) · 2023Observational
- Hemodynamic and Rhythmologic Effects of Push-Dose Landiolol in Critical Care-A Retrospective Cross-Sectional Study.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Elevation of serum lactate dehydrogenase during methylprednisolone pulse therapy as a predictor of high mortality in acute respiratory failure: A single-center, retrospective study.SAGE open medicine · 2023Article
- Antisynthetase syndrome sine myositis presenting as severe acute respiratory failure.BMJ case reports · 2022Article
- Association of Low Alanine Aminotransferase Values with Extubation Failure in Adult Critically Ill Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2021Article
- The comparison of GNRI and other nutritional indexes on short-term survival in geriatric patients treated for respiratory failure.Aging clinical and experimental research · 2021Article
- Long-stay patients in pediatric intensive care units. Five-years, 2-points, cross-sectional study.Saudi medical journal · 2020Article
- What are the prognostic factors affecting 30-day mortality in geriatric patients with respiratory failure in the Intensive Care Unit?Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReasons for the prolonged critical care support include uncertainty of outcome, the complex dynamic created between physicians with care team members and the patient's family over a general unwillingness to surrender to unfavorable outcomes. The purpose of this study was to investigate outcomes and identify risk factors of patients with acute respiratory failure (ARF) who required a prolonged intensive care unit (ICU) stay (≥21 days). It may provide reference to screen patients who are suitable for hospice care.
methodsThe medical records of all ARF patients with a prolonged ICU stay were retrospectively reviewed. The primary outcome was in-hospital mortality.
resultsWe identified 1,189 patients. Sepsis (n=896, 75.4%) was the most common cause of prolonged ICU stays, following by renal failure (n=232, 19.5%), and unstable hemodynamic status vasopressors or arrhythmia (n=208, 17.5%). Using multivariable logistic regression, we identified eight risk factors of death: age >75 years, ICU stay for more than 28 days, APACHE II score ≥25, unstable hemodynamic status, renal failure, hepatic failure, massive gastrointestinal tract bleeding, and using a fraction of inspired oxygen (FiO
conclusionsThe outcome of patients with ARF who required prolonged ICU stay was poor. They had a high risk of in-hospital mortality. Palliative care should be considered as a reasonable option for the patients at high risk of death.
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