Evidence map›Paper›PMID 31285802›Full record

ArticleInternational journal of organ transplantation medicine2019

Urinary CXCL9 and CXCL10 Levels and Acute Renal Graft Rejection.

H S Ciftci, T Tefik, M K Savran, E Demir, Y Caliskan, Y D Ogret, T Oktar, O Sanlı, T Kocak, Y Ozluk and 5 more

Abstract read
In one paragraph

Article in International journal of organ transplantation medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Article
  6. Immune Checkpoint Inhibitor Therapy for Kidney Transplant Recipients - A Review of Potential Complications and Management Strategies.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

H S CiftciDepartment of Medical Biology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
T TefikDepartment of Urology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
M K SavranDepartment of Anesthesia, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
E DemirDepartment of Nephrology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Y CaliskanDepartment of Nephrology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Y D OgretDepartment of Medical Biology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
T OktarDepartment of Urology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
O SanlıDepartment of Urology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
T KocakDepartment of Urology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Y OzlukDepartment of Pathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
F S OguzDepartment of Medical Biology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
I KilicaslanDepartment of Pathology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
F AydınDepartment of Medical Biology and Genetics, Faculty of Medicine, Istanbul Bilim University, Istanbul, Turkey.
A TurkmenDepartment of Nephrology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
I NaneDepartment of Urology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMonitoring of chemokines, CXCL9 and CXCL10, in serum may present a non-invasive detection method for rejection.

objectiveTo investigate the relationship between urinary levels of CXCL9 and CXCL10 and graft function following renal transplantation.

methods75 living-related donor renal transplant recipients were studied. Urinary levels of chemokines were collected pre-operatively, on post-operative 1

resultsClinical variables were monitored. 10 (15%) patients had biopsy-proven rejection during the follow-up period. The urinary CXCL9 level in those with rejection was significantly higher than that in those with non-rejection group at the 1

conclusionUrinary CXCL9 and CXCL10 levels might have a predictive value for T cell-mediated rejection in early post-transplantation period. Measurement of urinary CXCL9 and CXCL10 levels could provide an additional tool for the diagnosis of rejection.

Indexed as

BiomarkerChemokinesGraft functionRejectionRenal transplantation

Identifiers

PMID31285802
PMCPMC6604756

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.