Evidence map›Paper›PMID 31285786›Full record

ArticleOxidative medicine and cellular longevity2019

Ethanolic Extract of

David Tsuyoshi Hiramatsu Castro, Jaqueline Ferreira Campos, Marcio José Damião, Heron Fernandes Vieira Torquato, Edgar Julian Paredes-Gamero, Carlos Alexandre Carollo, Elaine Guadelupe Rodrigues, Kely de Picoli Souza, Edson Lucas Dos Santos

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Antimelanoma potential of natural compounds derived from plants: a systematic review of in vivo studies of B16 melanoma and its sublines.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Cytotoxicity and apoptotic effects of the ethyl acetate fraction ofContemporary oncology (Poznan, Poland) · 2025
    Article
  6. Chemical Composition, Antioxidant, and Cytotoxic Effects ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  7. Review
  8. Article
  9. An Insight into Anticancer Effect of Propolis and Its Constituents: A Review of Molecular Mechanisms.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

David Tsuyoshi Hiramatsu CastroResearch Group on Biotechnology and Bioprospecting Applied to Metabolism (GEBBAM), Federal University of Grande Dourados, Dourados, CEP: 79804-970 MS, Brazil.
Jaqueline Ferreira CamposResearch Group on Biotechnology and Bioprospecting Applied to Metabolism (GEBBAM), Federal University of Grande Dourados, Dourados, CEP: 79804-970 MS, Brazil.
Marcio José DamiãoResearch Group on Biotechnology and Bioprospecting Applied to Metabolism (GEBBAM), Federal University of Grande Dourados, Dourados, CEP: 79804-970 MS, Brazil.
Heron Fernandes Vieira TorquatoDepartment of Biochemistry, Federal University of São Paulo, São Paulo, CEP: 04044-020, SP, Brazil.
Edgar Julian Paredes-GameroDepartment of Biochemistry, Federal University of São Paulo, São Paulo, CEP: 04044-020, SP, Brazil.
Carlos Alexandre CarolloLaboratory of Natural Products and Mass Spectrometry, Federal University of Mato Grosso do Sul, Campo Grande, CEP: 79070-900 MS, Brazil.ORCID 0000-0003-1231-9441
Elaine Guadelupe RodriguesDepartment of Microbiology, Immunology, and Parasitology, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo, CEP: 04023-062 SP, Brazil.
Kely de Picoli SouzaResearch Group on Biotechnology and Bioprospecting Applied to Metabolism (GEBBAM), Federal University of Grande Dourados, Dourados, CEP: 79804-970 MS, Brazil.ORCID 0000-0001-5764-2125
Edson Lucas Dos SantosResearch Group on Biotechnology and Bioprospecting Applied to Metabolism (GEBBAM), Federal University of Grande Dourados, Dourados, CEP: 79804-970 MS, Brazil.ORCID 0000-0002-6557-7914
Universidade Federal da Grande Dourados · BRUniversidade Federal de Mato Grosso do Sul · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous melanoma is among the most aggressive types of cancer, and its rate of occurrence increases every year. Current pharmacological treatments for melanoma are not completely effective, requiring the identification of new drugs. As an alternative, plant-derived natural compounds are described as promising sources of new anticancer drugs. In this context, the objectives of this study were to identify the chemical composition of the ethanolic extract of

Indexed as

AnimalsAntineoplastic Agents, PhytogenicCell Cycle CheckpointsCell DeathCell Line, TumorCell ProliferationCell SurvivalCutaneous Malignant MelanomaDNA FragmentationEthanolMaleMelanomaMelanoma, ExperimentalMiceMice, Inbred C57BLPlant ExtractsAntineoplastic Agents, PhytogenicEthanolPlant Extracts

Identifiers

PMID31285786
PMCPMC6594258
OpenAlexW2951600526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.