Evidence map›Paper›PMID 31285775›Full record

ArticleTheranostics2019

Total internal reflection-based single-vesicle in situ quantitative and stoichiometric analysis of tumor-derived exosomal microRNAs for diagnosis and treatment monitoring.

Dinggeng He, Huizhen Wang, See-Lok Ho, Hei-Nga Chan, Luo Hai, Xiaoxiao He, Kemin Wang, Hung-Wing Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.

  1. Pooled it
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  14. TcEVdb: a database for T-cell-derived small extracellular vesicles from single-cell transcriptomes.Database : the journal of biological databases and curation · 2025
    Article
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  18. Extracellular Vesicle Preparation and Analysis: A State-of-the-Art Review.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Dinggeng HeDepartment of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
Huizhen WangState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Hunan University, Changsha, China.
See-Lok HoDepartment of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
Hei-Nga ChanDepartment of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
Luo HaiState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Hunan University, Changsha, China.
Xiaoxiao HeState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Hunan University, Changsha, China.
Kemin WangState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Hunan University, Changsha, China.
Hung-Wing LiDepartment of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
Hunan University · CNHong Kong Baptist University · HKState Key Laboratory of Chemobiosensing and Chemometrics

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Monitoring, PhysiologicAnimalsCell Line, TumorDisease Models, AnimalDNA, CatalyticExosomesHumansMaleMice, Inbred BALB CMicroRNAsNeoplasmsDNA, CatalyticMicroRNAsexosomesin situ quantitative and stoichiometric analysismiRNAssingle-vesicle imagingtotal internal reflection

Identifiers

PMID31285775
PMCPMC6599656
OpenAlexW2950372989

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.