Evidence map›Paper›PMID 31285760›Full record

ArticleTheranostics2019

Dual-Channel Fluorescence Imaging of Hydrogel Degradation and Tissue Regeneration in the Brain.

G Kate Park, Su-Hwan Kim, Kyungmin Kim, Priyanka Das, Byung-Gee Kim, Satoshi Kashiwagi, Hak Soo Choi, Nathaniel S Hwang

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  3. Review
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  8. Article
  9. Article
  10. Review
  11. Light-Triggered In Situ Biosynthesis of Artificial Melanin for Skin Protection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  12. Protein Based Biomaterials for Therapeutic and Diagnostic Applications.Progress in biomedical engineering (Bristol, England) · 2022
    Article
  13. In Vivo Imaging of Implanted Hyaluronic Acid Hydrogel Biodegradation.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  14. Detecting and Monitoring Hydrogels with Medical Imaging.ACS biomaterials science & engineering · 2021
    Review
  15. Theranostic biomaterials for tissue engineering.Current opinion in biomedical engineering · 2021
    Article
  16. Article
  17. Review
  18. Synthesis of poly(RSC advances · 2020
    Article
  19. Article
  20. Targeted Near-Infrared Fluorescence Imaging for Regenerative Medicine.Tissue engineering and regenerative medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

G Kate ParkInterdisciplinary Program in Bioengineering, Seoul National University, Seoul 151-742, South Korea.
Su-Hwan KimSchool of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 151-742, South Korea.
Kyungmin KimSchool of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 151-742, South Korea.
Priyanka DasGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Byung-Gee KimInterdisciplinary Program in Bioengineering, Seoul National University, Seoul 151-742, South Korea.
Satoshi KashiwagiGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Hak Soo ChoiGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Nathaniel S HwangInterdisciplinary Program in Bioengineering, Seoul National University, Seoul 151-742, South Korea.
Gordon Center for Medical Imaging · USSeoul National University · KRHarvard University · USMassachusetts General Hospital · US

Funding

Image-Guided Drug Delivery for Pancreatic Neuroendocrine Tumor.R01EB022230 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI CHOI, HAK SOO, HENARY, MAGED M · 2017 to 2020
$3.6M
Nanochelation Therapies for Iron Overload DisordersR01HL143020 · NHLBI · UNIVERSITY OF MASSACHUSETTS LOWELL · PI CHOI, HAK SOO, KIM, JONGHAN · 2018 to 2021
$2.6M
Image-Guided Drug Delivery and Treatment for GISTR21CA223270 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CHOI, HAK SOO · 2018 to 2019
$398k
NCI NIH HHS R21 CA223270NHLBI NIH HHS R01 HL143020NIBIB NIH HHS R01 EB022230
6 · The paper itself

Abstract

The ability of brain tissue to regenerate is limited; therefore, brain diseases (i.e., trauma, stroke, tumors) often lead to irreversible motor and cognitive impairments. Therapeutic interventions using various types of injectable biomaterials have been investigated to promote endogenous neural differentiation. Despite promising results in pre-clinical studies, the translation of regenerative medicine to the clinic has many challenges due to the lack of reliable imaging systems to achieve accurate evaluation of the treatment efficacy.

Indexed as

AnimalsBrainFluorescenceGelatinHyaluronic AcidHydrogelsMiceMice, Inbred C57BLOptical ImagingRegenerationTissue ScaffoldsGelatinHyaluronic AcidHydrogelshylanBrain tissue regenerationFluorescence imagingMultichannel imagingNIR injectable hydrogel

Identifiers

PMID31285760
PMCPMC6599647
OpenAlexW2952092009

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.