Observational studyCurrent oncology (Toronto, Ont.)2019
Association of preoperative anemia and perioperative allogenic red blood cell transfusion with oncologic outcomes in patients with nonmetastatic colorectal cancer.
Observational study in Current oncology (Toronto, Ont.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 48 citations in OpenAlex.
- Development and Validation of a Predictive Risk Score for Blood Transfusion in Patients Undergoing Curative-Intent Surgery for Intrahepatic Cholangiocarcinoma.Journal of surgical oncology · 2025Article
- An overview of the current evidences on the role of iron in colorectal cancer: a review.Frontiers in oncology · 2025Review
- Article
- Predicting blood transfusion needs in colorectal surgery at a university hospital in Saudi Arabia: insights into anemia, malnutrition, and surgical factors.Perioperative medicine (London, England) · 2024Article
- Preoperative intravenous iron treatment - a cohort study on colorectal cancer recurrence.Surgery open science · 2023Article
- A novel prognostic model to predict OS and DFS of stage II/III gastric adenocarcinoma patients in China.Heliyon · 2022Article
- Effect of a Patient Blood Management system on perioperative transfusion practice and short-term outcomes of colorectal cancer surgery.Blood transfusion = Trasfusione del sangue · 2022Article
- Effect of peri-operative blood transfusions on long-term prognosis of patients with colorectal cancer.Blood transfusion = Trasfusione del sangue · 2022Article
- Preoperative intravenous iron treatment reduces postoperative complications and postoperative anemia in preoperatively anemic patients with colon carcinoma.International journal of colorectal disease · 2022Article
- The impact of perioperative red blood cell transfusion on the prognosis of colorectal cancer.Frontiers in surgery · 2022Article
- Do Preoperative Transfusions Impact Prognosis in Moderate to Severe Anaemic Surgical Patients with Colon Cancer?Current oncology (Toronto, Ont.) · 2021Article
- Does delaying curative surgery for colorectal cancer influence long-term disease-free survival? A cohort study.Langenbeck's archives of surgery · 2021Article
- Need for preoperative anemia management clinics in Japan: initiatives at a university hospital in the USA.Journal of anesthesia · 2021Article
- Preoperative Transfusion for Anemia in Patients Undergoing Abdominal Surgery for Malignancy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Preoperative rectal tumor embolization as an adjunctive tool for bloodless abdominoperineal excision: A case report.World journal of clinical oncology · 2020Article
- Correlation between hematological parameters and outcome in patients with locally advanced cervical cancer treated by concomitant chemoradiotherapy.Cancer medicine · 2020Article
- Use of intravenous iron therapy in colorectal cancer patient with iron deficiency anemia: a propensity-score matched study.International journal of colorectal disease · 2020Article
- Prognostic evaluation of colorectal cancer using three new comprehensive indexes related to infection, anemia and coagulation derived from peripheral blood.Journal of Cancer · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: We investigated whether preoperative anemia and perioperative blood transfusion (pbt) are associated with overall survival and recurrence-free survival in patients with nonmetastatic colorectal cancer. Methods: From 1 January 2009 to 31 December 2014, 1003 patients with primary colorectal cancer were enrolled in the study. Perioperative clinical and oncologic outcomes were analyzed based on the presence of preoperative anemia and pbt. Results: Preoperative anemia was found in 468 patients (46.7%). In the anemia and no-anemia groups, pbt was performed in 44% and 15% of patients respectively. Independent predictors for pbt were preoperative anemia, higher American Society of Anesthesiologists score, laparotomy, lengthy operative time, advanced TNM stage, T4 stage, and 30-day morbidity. The use of pbt, but not preoperative anemia, was found to be an independent adverse prognostic factor for overall survival. In terms of recurrence-free survival, the presence of preoperative anemia was similarly not a significant prognostic factor, but the use of pbt was an independent factor for an unfavourable prognosis. Conclusions: The use of pbt, but not preoperative anemia, was independently associated with worse overall and recurrence-free survival in nonmetastatic colorectal cancer. For better oncologic outcomes, our findings indicate a need to reduce the use of blood transfusion during the perioperative period.
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