Evidence map›Paper›PMID 31285535›Full record

ArticleMucosal immunology2019

JunB plays a crucial role in development of regulatory T cells by promoting IL-2 signaling.

Takaharu Katagiri, Soh Yamazaki, Yuto Fukui, Kotaro Aoki, Hideo Yagita, Takashi Nishina, Tetuo Mikami, Sayaka Katagiri, Ayako Shiraishi, Soichiro Kimura and 5 more

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Mucosal immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. JunB-HBZ nuclear translocation by TGF-β is a key driver in HTLV-1-mediated leukemogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. NAR genomics and bioinformatics · 2023
    Article
  10. JunB: a paradigm for Jun family in immune response and cancer.Frontiers in cellular and infection microbiology · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Takaharu KatagiriDepartment of Biochemistry, Toho University School of Medicine, 5-21-16 Omorinishi, Ota-ku, Tokyo, 143-8540, Japan.
Soh YamazakiDepartment of Biochemistry, Toho University School of Medicine, 5-21-16 Omorinishi, Ota-ku, Tokyo, 143-8540, Japan. syamaz@med.toho-u.ac.jp.
Yuto FukuiDepartment of Microbiology and Infectious Diseases, Toho University School of Medicine, 5-21-16 Omorinishi, Ota-ku, Tokyo, 143-8540, Japan.
Kotaro AokiDepartment of Microbiology and Infectious Diseases, Toho University School of Medicine, 5-21-16 Omorinishi, Ota-ku, Tokyo, 143-8540, Japan.
Hideo YagitaDepartment of Immunology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan.
Takashi NishinaDepartment of Biochemistry, Toho University School of Medicine, 5-21-16 Omorinishi, Ota-ku, Tokyo, 143-8540, Japan.
Tetuo MikamiDepartment of Pathology, Toho University School of Medicine, 5-21-16 Omorinishi, Ota-ku, Tokyo, 143-8540, Japan.
Sayaka KatagiriDepartment of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan.
Ayako ShiraishiDepartment of Biochemistry, Toho University School of Medicine, 5-21-16 Omorinishi, Ota-ku, Tokyo, 143-8540, Japan.
Soichiro KimuraDepartment of Microbiology and Infectious Diseases, Toho University School of Medicine, 5-21-16 Omorinishi, Ota-ku, Tokyo, 143-8540, Japan.
Kazuhiro TatedaDepartment of Microbiology and Infectious Diseases, Toho University School of Medicine, 5-21-16 Omorinishi, Ota-ku, Tokyo, 143-8540, Japan.
Hideki SumimotoDepartment of Biochemistry, Kyushu University Graduate School of Medical Sciences, Fukuoka, 812-8582, Japan.
Shogo EndoAging Neuroscience Research Team, Tokyo Metropolitan Institute of Gerontology, Tokyo, 173-0015, Japan.
Hideto KamedaDivision of Rheumatology, Department of Internal Medicine, Toho University Graduate School of Medicine (Ohashi Medical Center), 2-22-36 Ohashi, Meguro-ku, Tokyo, 153-8515, Japan.
Hiroyasu NakanoDepartment of Biochemistry, Toho University School of Medicine, 5-21-16 Omorinishi, Ota-ku, Tokyo, 143-8540, Japan. hiroyasu.nakano@med.toho-u.ac.jp.
Toho University · JPJuntendo University · JPKyushu University · JPTokyo Medical and Dental University · JPTokyo Metropolitan Institute of Gerontology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The AP-1 transcription factor JunB plays crucial roles in multiple biological processes, including placental formation and bone homeostasis. We recently reported that JunB is essential for development of Th17 cells, and thus Junb-deficient mice are resistant to experimental autoimmune encephalomyelitis. However, the role of JunB in CD4

Indexed as

Signal TransductionAnimalsBinding SitesColitisDextran SulfateDisease Models, AnimalGene Expression ProfilingGene Expression RegulationInterferon-gammaInterleukin-2MiceMice, TransgenicProtein BindingT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsTranscription FactorsDextran SulfateInterferon-gammaInterleukin-2JunB protein, humanTranscription Factors

Identifiers

PMID31285535
OpenAlexW2954897881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.