Evidence map›Paper›PMID 31285470›Full record

ArticleScientific reports2019

Multiple Pleomorphic Tetramers of Thermostable Direct Hemolysin from Grimontia hollisae in Exerting Hemolysis and Membrane Binding.

Yu-Kuo Wang, Sheng-Cih Huang, Chin-Yuan Chang, Wan-Ting Huang, Man-Jun Liao, Bak-Sau Yip, Feng-Pai Chou, Thomas Tien-Hsiung Li, Tung-Kung Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yu-Kuo WangDepartment of Biological Science and Technology, National Chiao Tung University, Hsin-Chu, 30010, Taiwan, Republic of China.
Sheng-Cih HuangDepartment of Biological Science and Technology, National Chiao Tung University, Hsin-Chu, 30010, Taiwan, Republic of China.
Chin-Yuan ChangDepartment of Biological Science and Technology, National Chiao Tung University, Hsin-Chu, 30010, Taiwan, Republic of China.
Wan-Ting HuangDepartment of Biological Science and Technology, National Chiao Tung University, Hsin-Chu, 30010, Taiwan, Republic of China.
Man-Jun LiaoDepartment of Biological Science and Technology, National Chiao Tung University, Hsin-Chu, 30010, Taiwan, Republic of China.
Bak-Sau YipDepartment of Neurology, National Taiwan University Hospital, Hsin-Chu, 30059, Taiwan, Republic of China.
Feng-Pai ChouDepartment of Biological Science and Technology, National Chiao Tung University, Hsin-Chu, 30010, Taiwan, Republic of China.
Thomas Tien-Hsiung LiGraduate Institute of Biochemistry, National Chung Hsing University, Taichung, 40227, Taiwan, Republic of China. lithomas@dragon.nchc.edu.tw.
Tung-Kung WuDepartment of Biological Science and Technology, National Chiao Tung University, Hsin-Chu, 30010, Taiwan, Republic of China. tkwmll@mail.nctu.edu.tw.ORCID http://orcid.org/0000-0002-6478-7768
National Yang Ming Chiao Tung University · TWNational Chung Hsing University · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oligomerization of protein into specific quaternary structures plays important biological functions, including regulation of gene expression, enzymes activity, and cell-cell interactions. Here, we report the determination of two crystal structures of the Grimontia hollisae (formally described as Vibrio hollisae) thermostable direct hemolysin (Gh-TDH), a pore-forming toxin. The toxin crystalized in the same space group of P2

Indexed as

AnimalsBacterial ProteinsBacterial ToxinsCell MembraneCrystallography, X-RayHeLa CellsHemolysin ProteinsHemolysisHumansModels, MolecularMutagenesis, Site-DirectedProtein BindingProtein MultimerizationProtein Structure, QuaternaryRabbitsVibrionaceaeBacterial ProteinsBacterial ToxinsHemolysin Proteinsthermostable direct hemolysin

Identifiers

PMID31285470
PMCPMC6614540
OpenAlexW2959665798

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.