Evidence map›Paper›PMID 31285395›Full record

ArticlePediatrics2019

Neuropsychiatric Sequelae in Adolescents With Acute Synthetic Cannabinoid Toxicity.

Sarah Ann R Anderson, Anna M Oprescu, Diane Calello, Andrew Monte, Peter S Dayan, Yasmin L Hurd, Alex F Manini, ToxIC Investigators

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Association of cannabis, cannabidiol and synthetic cannabinoid use with mental health in UK adolescents.The British journal of psychiatry : the journal of mental science · 2023
    Article
  4. Article
  5. Correction to: The Potential Proconvulsant Effects of Cannabis: a Scoping Review.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2023
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Sarah Ann R AndersonDepartments of Pediatrics and sra2146@cumc.columbia.edu.
Anna M OprescuDepartments of Psychiatry, Neuroscience, and Pharmacological Science, Icahn School of Medicine at Mount Sinai, New York, New York.
Diane CalelloDepartment of Emergency Medicine, New Jersey Medical School, Rutgers University, Newark, New Jersey; and.
Andrew MonteDepartments of Emergency Medicine and Pharmaceutical Sciences, School of Medicine, University of Colorado, Aurora, Colorado.
Peter S DayanDepartments of Pediatrics and.
Yasmin L HurdDepartments of Psychiatry, Neuroscience, and Pharmacological Science, Icahn School of Medicine at Mount Sinai, New York, New York.
Alex F ManiniDivision of Medical Toxicology, Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai and Elmhurst Hospital Center, New York, New York.
ToxIC Investigators
Icahn School of Medicine at Mount Sinai · USColumbia University Irving Medical Center · USRutgers, The State University of New Jersey · USUniversity of Colorado Anschutz Medical Campus · US

Funding

An Integrated Approach to Personalized MedicineK23GM110516 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI MONTE, ANDREW ALBERT · 2014 to 2016
$588k
NIGMS NIH HHS K23 GM110516
6 · The paper itself

Abstract

BACKGROUND AND

objectivesAdolescents represent the largest age group that presents to emergency departments (ED) for synthetic cannabinoid (SC) toxicity; however, the neurotoxic effects of acute SC exposures in this group are understudied. Our aim was to characterize the neuropsychiatric presentation of adolescents with SC-related exposure in the ED compared with those with traditional cannabis exposure.

methodsA multicenter registry of clinical information prospectively collected by medical toxicologists (Toxicology Investigators Consortium Case Registry) was reviewed for adolescents presenting to the ED after SC or cannabis exposure from 2010 through 2018. Associations were measured between drug exposures and neuropsychiatric symptoms and/or signs. Exposures were classified into 4 groups: SC-only exposure, SC-polydrug exposures, cannabis-only exposure, and cannabis-polydrug exposures.

resultsAdolescents presenting to the ED with SC-only exposure (

conclusionsIn this multisite cohort of US adolescents assessed in the ED, SC exposure was associated with higher odds of neuropsychiatric morbidity than cannabis exposure providing a distinct neurospychiatric profile of acute SC toxicity in adolescents.

Indexed as

AdolescentCannabinoidsEmergency Service, HospitalFemaleHumansMaleMarijuana AbuseMental DisordersRegistriesYoung AdultCannabinoids

Identifiers

PMID31285395
PMCPMC6697124
OpenAlexW2960072765

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.