Evidence map›Paper›PMID 31285265›Full record

ArticleThe Journal of biological chemistry2019

Phosphomimetic substitution at Ser-33 of the chloroquine resistance transporter PfCRT reconstitutes drug responses in

Cecilia P Sanchez, Sonia Moliner Cubel, Britta Nyboer, Monika Jankowska-Döllken, Christine Schaeffer-Reiss, Daniel Ayoub, Gabrielle Planelles, Michael Lanzer

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  5. The phosphorylation of serineMatrix biology : journal of the International Society for Matrix Biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Cecilia P SanchezCenter of Infectious Diseases, Parasitology, Heidelberg University Hospital, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Sonia Moliner CubelCenter of Infectious Diseases, Parasitology, Heidelberg University Hospital, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Britta NyboerCenter of Infectious Diseases, Parasitology, Heidelberg University Hospital, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Monika Jankowska-DöllkenCenter of Infectious Diseases, Parasitology, Heidelberg University Hospital, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Christine Schaeffer-ReissLaboratoire de Spectrométrie de Masse BioOrganique, Université de Strasbourg, CNRS, Institut Pluridisciplinaire Hubert Curien (IPHC) UMR 7178, 67037 Strasbourg, France.
Daniel AyoubLaboratoire de Spectrométrie de Masse BioOrganique, Université de Strasbourg, CNRS, Institut Pluridisciplinaire Hubert Curien (IPHC) UMR 7178, 67037 Strasbourg, France.
Gabrielle PlanellesINSERM, Centre de Recherche des Cordeliers, Unité 1138, CNRS, ERL8228, Université Pierre et Marie Curie and Université Paris-Descartes, 75006 Paris, France.
Michael LanzerCenter of Infectious Diseases, Parasitology, Heidelberg University Hospital, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany michael.lanzer@med.uni-heidelberg.de.ORCID 0000-0002-0220-6526
Heidelberg University · DECentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The chloroquine resistance transporter PfCRT of the human malaria parasite

Indexed as

AntimalarialsChloroquineDrug ResistanceKineticsMembrane Transport ProteinsParasitic Sensitivity TestsPhosphorylationPlasmodium falciparumProtozoan ProteinsSerineAntimalarialsChloroquineMembrane Transport ProteinsPfCRT protein, Plasmodium falciparumProtozoan ProteinsSerinedrug resistancedrug transportgenome editingkinase inhibitorskineticsPfCRTphosphorylationPlasmodiumtransport velocityvirulence factor

Identifiers

PMID31285265
PMCPMC6709616
OpenAlexW2960273830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.