Evidence map›Paper›PMID 31284660›Full record

ReviewCells2019

The Role of Phosphatases in Nuclear Envelope Disassembly and Reassembly and Their Relevance to Pathologies.

Florentin Huguet, Shane Flynn, Paola Vagnarelli

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Analog-sensitive Cdk1 as a tool to study mitotic exit: protein phosphatase 1 is required downstream from Cdk1 inactivation in budding yeast.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. The Dynamics of Lamin a During the Cell Cycle.Frontiers in molecular biosciences · 2021
    Article
  12. Review
  13. Article
  14. Enzymatic Noncovalent Synthesis.Chemical reviews · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Membrane and organelle dynamics during cell division.Nature reviews. Molecular cell biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Florentin HuguetCollege of Health and Life Science, Research Institute for Environment Health and Society, Brunel University London, London UB8 3PH, UK.
Shane FlynnCollege of Health and Life Science, Research Institute for Environment Health and Society, Brunel University London, London UB8 3PH, UK.
Paola VagnarelliCollege of Health and Life Science, Research Institute for Environment Health and Society, Brunel University London, London UB8 3PH, UK. Paola.Vagnarelli@Brunel.ac.uk.ORCID 0000-0002-0000-2271
Brunel University of London · GB

Funding

Wellcome Trust 210742/Z/18/Z
6 · The paper itself

Abstract

The role of kinases in the regulation of cell cycle transitions is very well established, however, over the past decade, studies have identified the ever-growing importance of phosphatases in these processes. It is well-known that an intact or otherwise non-deformed nuclear envelope (NE) is essential for maintaining healthy cells and any deviation from this can result in pathological conditions. This review aims at assessing the current understanding of how phosphatases contribute to the remodelling of the nuclear envelope during its disassembling and reformation after cell division and how errors in this process may lead to the development of diseases.

Indexed as

Cell Cycle CheckpointsMitosisChromatinHumansNuclear EnvelopePhosphoric Monoester HydrolasesProtein Interaction MapsChromatinPhosphoric Monoester Hydrolasescyclin dependent kinase (CDK)micronuclei (MN)nuclear envelope (NE)nuclear laminanuclear pore complex (NPC)polo-like kinase (PLK)protein phosphatase

Identifiers

PMID31284660
PMCPMC6678589
OpenAlexW2955109164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.