Evidence map›Paper›PMID 31284507›Full record

ReviewFoods (Basel, Switzerland)2019

Rapid Solid-Liquid Dynamic Extraction (RSLDE): A Powerful and Greener Alternative to the Latest Solid-Liquid Extraction Techniques.

Daniele Naviglio, Pierpaolo Scarano, Martina Ciaravolo, Monica Gallo

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Bioactive Peptides From theFood science & nutrition · 2026
    Review
  2. Naturally Colored ZrOMolecules (Basel, Switzerland) · 2026
    Article
  3. Quinoa (International journal of molecular sciences · 2026
    Review
  4. A deep dive into herbal extraction: Techniques, trends, and technological advancements.South African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Phycocyanin extraction fromCurrent research in food science · 2025
    Review
  10. Foods (Basel, Switzerland) · 2024
    Article
  11. Valorization of Potato Peels (Foods (Basel, Switzerland) · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Coriander (Molecules (Basel, Switzerland) · 2023
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniele NaviglioDepartment of Chemical Sciences, University of Naples Federico II, via Cintia; Monte S. Angelo Complex, Naples 80126, Italy.
Pierpaolo ScaranoDepartment of Science and Technology, University of Sannio, Via Port'Arsa 11, 82100 Benevento, Italy.
Martina CiaravoloDepartment of Chemical Sciences, University of Naples Federico II, via Cintia; Monte S. Angelo Complex, Naples 80126, Italy.
Monica GalloDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, via Pansini 5, Naples 80131, Italy. mongallo@unina.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditionally, solid-liquid extractions are performed using organic and/or inorganic liquids and their mixtures as extractant solvents in contact with an insoluble solid matrix (e.g., the Soxhlet method) or using sequential atmospheric pressure systems that require long procedures, such as maceration or percolation. The objective of this procedure is the extraction of any compounds that can be carried out from the inner solid material to the outlet, resulting in a solution containing colorants, bioactive compounds, odorous substances, etc. Over the years, in the extraction techniques sector, there have been many important changes from the points of view of production, quality, and human and environmental safety due to improvements in technology. In more recent times, the interest of the scientific community has been aimed at the study of sustainable processes for the valorization of extracts from vegetables and food by-products, through the use of non-conventional (innovative) technologies that represent a valid alternative to conventional methods, generally through saving time and energy and the formation of fewer by-products. Therefore, with the development of principles based on the prevention of pollution, on a lower risk for human health, and on a low environmental impact, new systems have been implemented to reduce extraction times and solvent consumption, to improve efficiency, and to increase the productivity of the extracts. From this point of view, rapid solid-liquid dynamic extraction (RSLDE), performed using the Naviglio extractor, compared to traditional applications, is a technique that is able to reduce extraction times, generally leads to higher yields, does not require heating of the system, allows one to extract the active ingredients, and avoids their degradation. This technique is based on a new solid-liquid extraction principle named Naviglio's principle. In this review, after reviewing the latest extraction techniques, an overview of RSLDE applications in various research and production sectors over the past two decades is provided.

Indexed as

bioactive compoundsgreen extractionNaviglio extractorNaviglio’s principleRSLDEsolid-liquid extraction

Identifiers

PMID31284507
PMCPMC6678328

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.