ArticleEnvironment international2019
Relationship between Pb relative bioavailability and bioaccessibility in phosphate amended soil: Uncertainty associated with predicting Pb immobilization efficacy using in vitro assays.
Article in Environment international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 39 citations in OpenAlex.
- Arsenic, cadmium, lead, antimony bioaccessibility and relative bioavailability in legacy gold mining waste.Journal of hazardous materials · 2024Article
- Remediation options to reduce bioaccessible and bioavailable lead and arsenic at a smelter impacted site - consideration of treatment efficacy.Environmental pollution (Barking, Essex : 1987) · 2024Article
- Successful Conversion of Pb-Contaminated Soils to Low-Bioaccessibility Plumbojarosite Using Potassium-Jarosite at Ambient Temperature.Environmental science & technology · 2022Article
- Article
- Improving the predictive value of bioaccessibility assays and their use to provide mechanistic insights into bioavailability for toxic metals/metalloids - A research prospectus.Journal of toxicology and environmental health. Part B, Critical reviews · 2021Review
- Plumbojarosite formation in contaminated soil to mitigate childhood exposure to lead, arsenic and antimony.Journal of hazardous materials · 2021Article
- Combined application of Bacillus sp. MN-54 and phosphorus improved growth and reduced lead uptake by maize in the lead-contaminated soil.Environmental science and pollution research international · 2020Article
- Lead source and bioaccessibility in windowsill dusts within a Pb smelting-affected area.Environmental pollution (Barking, Essex : 1987) · 2020Article
- Plastic, nutrition and pollution; relationships between ingested plastic and metal concentrations in the livers of two Pachyptila seabirds.Scientific reports · 2020Article
- Correlation between lead speciation and inhalation bioaccessibility using two different simulated lung fluids.Environmental pollution (Barking, Essex : 1987) · 2020Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
In this study, an in vitro in vivo correlation (IVIVC) between Pb in vitro bioaccessibility (IVBA) and relative bioavailability (RBA) was explored to determine whether the efficacy of Pb immobilization in phosphate amended soils could be predicted using an in vitro approach. Mining/smelting impacted soil from Broken Hill, Australia (582-3536 mg/kg of Pb in the <250 μm soil particle fraction) was amended with Phosphoric Acid (PA), Mono Ammonium Phosphate (MAP) or Triple Super Phosphate (TSP) at Pb:P molar ratios of 1:1-1:5. Pb speciation in pre- and post-treated soil was assessed using X-ray Absorption Spectroscopy (XAS), Pb IVBA was measured using the Solubility Bioaccessibility Research Consortium (SBRC) assay (gastric and intestinal phases), and Pb RBA was determined in mice using blood Pb concentration as the bioavailability endpoint. XAS analysis revealed a 3.75-6.00 fold increase in the weighted % of Pb phosphates in soil containing >1000 mg/kg Pb while treatment effect ratios of 0.89-0.99 (SBRC-G), 0.09-0.71 (SBRC-I) and 0.27-0.80 (RBA) were observed in PA amended soil (Pb:P = 1:5). Although significant (p < 0.05) correlation were obtained between Pb RBA and IVBA (%) determined using SBRC-G (r = 0.64) and SBRC-I (r = 0.67), the strengths of the relationships were weak (r
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Registered trials
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